Table 9.6h

Persistency of Discharge Regimen by Follow-up Period, 2001 to 2005

Recipients with Liver Transplants

  Year of Transplant
2001 2002 2003 2004 2005
Discharge Regimen (w/ or w/o Steroid Use) CyA+Aza At Discharge (N) 53 64 28 57 14
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 64.2% 26.6% 17.9% 43.9% 35.7%
1 Year PostTx (%) 49.1% 12.5% 7.1% 28.1% 11.9%
2 Years PostTx (%) 9.4% 6.3% 3.6% 21.4% 11.9%
3 Years PostTx (%) 7.5% 4.7% 3.6% - -
CyA+MMF At Discharge (N) 251 228 214 232 215
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 61.2% 57.5% 57.9% 62.5% 72.7%
1 Year PostTx (%) 42.8% 35.4% 38.6% 47.7% 59.9%
2 Years PostTx (%) 29.3% 22.4% 28.7% 42.3% 56.1%
3 Years PostTx (%) 23.1% 20.0% 28.1% 31.8% -
CyA+Siro At Discharge (N) 34 28 26 27 34
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 39.4% 39.3% 56.0% 66.7% 58.8%
1 Year PostTx (%) 24.2% 25.0% 36.0% 27.5% 52.2%
2 Years PostTx (%) 15.2% 17.9% 24.0% 14.8% -
3 Years PostTx (%) 11.4% 7.1% 12.0% - -
Siro+MMF At Discharge (N) 47 50 48 46 51
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 61.7% 56.0% 64.6% 60.1% 76.0%
1 Year PostTx (%) 42.6% 30.2% 47.9% 35.6% 64.4%
2 Years PostTx (%) 27.7% 25.9% 39.0% 27.7% -
3 Years PostTx (%) 19.1% 23.7% 39.0% - -
Tac+Aza At Discharge (N) 65 96 105 52 23
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 56.9% 48.4% 50.5% 51.9% 69.6%
1 Year PostTx (%) 40.0% 33.4% 40.6% 36.5% 40.8%
2 Years PostTx (%) 28.8% 26.9% 30.5% 30.9% -
3 Years PostTx (%) 22.4% 18.3% 25.9% 10.3% -
Tac+MMF At Discharge (N) 1,665 1,862 2,347 2,671 3,097
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 70.0% 67.4% 68.4% 72.2% 79.2%
1 Year PostTx (%) 55.6% 50.3% 52.9% 57.9% 67.7%
2 Years PostTx (%) 38.9% 37.1% 41.9% 47.2% 58.1%
3 Years PostTx (%) 28.8% 30.9% 36.8% 35.0% -
Tac+Siro At Discharge (N) 251 142 62 102 62
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 62.3% 65.0% 45.2% 61.8% 70.0%
1 Year PostTx (%) 49.4% 47.7% 33.5% 40.7% 51.8%
2 Years PostTx (%) 32.6% 34.7% 28.5% 39.7% 0.0%
3 Years PostTx (%) 24.2% 26.7% 24.7% - 0.0%


Source: OPTN/SRTR Data as of May 1, 2007.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen (CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up period, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.