Table 9.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1996 to 2005

Recipients with Liver Transplants

  Year of Transplant
1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Transplants 4,083 4,188 4,516 4,751 4,995 5,191 5,331 5,673 6,169 6,441
Tx with Follow-up Immunosuppression Info 3,004 3,182 3,479 3,643 3,889 4,089 4,304 4,571 4,945 5,052
Corticosteroids Any in Category 94.8% 95.0% 93.0% 89.2% 90.5% 89.4% 87.2% 78.5% 75.3% 75.0%
Steroids 94.8% 95.0% 93.0% 89.2% 90.5% 89.4% 87.2% 78.5% 75.3% 75.0%
Cyclosporine Any in Category 42.3% 39.8% 33.4% 30.4% 23.3% 18.4% 14.0% 11.8% 11.4% 10.3%
Cyclosporin 0.0% 0.0% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.1%
Sandimmmune 8.8% 5.7% 7.0% 7.0% 5.4% 3.7% 2.0% 0.7% 0.8% 1.1%
Neoral 33.5% 34.1% 26.3% 23.3% 17.2% 13.2% 9.8% 8.9% 9.1% 7.7%
Gengraf 0.0% 0.0% 0.0% 0.1% 0.5% 1.3% 2.0% 1.8% 1.3% 1.3%
Eon 0.0% 0.0% 0.0% 0.0% 0.1% 0.2% 0.2% 0.3% 0.2% 0.1%
Tacrolimus Any in Category 64.3% 66.3% 73.4% 76.7% 84.2% 89.0% 90.5% 90.5% 89.7% 91.4%
Tacrolimus 64.3% 66.3% 73.4% 76.7% 84.2% 89.0% 90.5% 90.5% 89.7% 91.4%
Antimetabolites Any in Category 45.2% 44.4% 40.3% 49.2% 52.2% 53.5% 53.7% 55.1% 59.1% 66.1%
Mycophenolate Mofetil 23.9% 25.9% 29.7% 40.7% 46.3% 48.8% 49.3% 52.4% 55.6% 62.0%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.6% 2.9%
Azathioprine 21.2% 18.2% 10.5% 8.3% 5.9% 4.6% 4.3% 2.7% 2.9% 1.2%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Cytoxan 0.2% 0.3% 0.0% 0.1% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 0.0% 1.2% 3.2% 15.1% 16.7% 13.8% 12.2% 14.1% 13.8%
Sirolimus 0.0% 0.0% 1.2% 3.1% 15.1% 16.7% 13.8% 12.2% 14.1% 13.8%
Everolimus 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2007.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.