Your browser does not support JavaScript capabilities, which maybe required to display this page properly.


PDF FormatRequires Adobe Acrobat Reader

Table 8.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1998 to 2007

Recipients with Kidney-Pancreas Transplants

  Transplant Year
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Transplants 972 941 915 891 905 871 881 903 924 862
Functioning Graft at 1 Year PostTx 871 859 840 818 821 785 793 826 831 786
With Maintenance Use Recorded at 1 Year PostTx 632 839 809 798 797 779 788 816 813 755
CyA 0.2% 0.2% 0.0% 0.1% 0.3% 0.0% 0.0% 0.2% 0.1% 0.0%
Tac 0.9% 0.5% 0.1% 1.5% 2.6% 1.7% 2.8% 1.8% 2.0% 1.3%
--- + MMF/MPA 0.0% 0.0% 0.1% 0.1% 0.1% 0.4% 1.0% 0.2% 0.4% 0.0%
CyA + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.3% 0.5% 0.1% 1.0% 0.4% 0.9%
Tac + MMF/MPA 0.6% 1.0% 2.7% 2.1% 4.9% 6.3% 9.8% 14.2% 19.9% 20.4%
--- + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0%
CyA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0%
Tac + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.1% 0.0%
Tac + MMF/MPA + OtherAntimet 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + Siro/Evero 0.2% 0.0% 0.1% 0.1% 0.4% 0.3% 0.0% 0.0% 0.0% 0.0%
CyA + Siro/Evero 0.0% 0.0% 0.2% 0.1% 0.0% 1.0% 2.2% 1.8% 2.3% 2.0%
Tac + Siro/Evero 0.0% 0.0% 3.0% 5.3% 7.3% 8.2% 6.0% 8.2% 3.3% 3.2%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.1% 0.0% 1.5% 3.9% 1.5% 1.0% 0.7%
CyA + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.3% 0.1% 0.0% 0.0%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.1% 1.5% 0.9% 1.2% 1.0% 1.3% 3.2% 3.8%
Tac + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.1% 0.0%
--- + Steroids 0.3% 0.2% 0.4% 0.1% 1.3% 0.5% 0.5% 0.1% 0.4% 0.4%
CyA + Steroids 1.6% 1.9% 1.7% 1.1% 0.5% 0.4% 0.1% 0.1% 0.2% 0.1%
Tac + Steroids 5.1% 6.0% 4.0% 5.1% 4.4% 5.0% 2.7% 4.5% 3.6% 4.5%
--- + MMF/MPA + Steroids 0.6% 0.4% 0.4% 0.4% 0.5% 0.4% 0.8% 0.6% 0.4% 0.7%
CyA + MMF/MPA + Steroids 24.1% 18.6% 11.5% 8.3% 8.8% 6.8% 3.2% 2.3% 2.0% 2.6%
Tac + MMF/MPA + Steroids 54.7% 57.6% 56.1% 52.0% 50.7% 52.1% 55.1% 54.0% 52.9% 53.5%
--- + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0%
CyA + OtherAntimet + Steroids 2.1% 0.1% 0.4% 0.1% 0.4% 0.0% 0.3% 0.0% 0.0% 0.3%
Tac + OtherAntimet + Steroids 3.6% 3.7% 1.7% 0.8% 1.5% 1.7% 1.0% 0.6% 1.2% 0.9%
--- + Siro/Evero + Steroids 0.0% 0.2% 0.5% 0.4% 0.3% 0.6% 0.3% 0.0% 0.1% 0.3%
CyA + Siro/Evero + Steroids 0.0% 0.5% 3.0% 2.5% 1.0% 1.5% 0.5% 0.6% 0.6% 0.8%
Tac + Siro/Evero + Steroids 0.0% 1.5% 6.6% 12.8% 9.9% 5.5% 5.2% 4.0% 3.2% 2.5%
Other Regimen 6.0% 7.6% 7.3% 5.4% 4.1% 4.1% 3.2% 2.3% 2.3% 1.1%


Source: OPTN/SRTR Data as of May 4, 2009.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.



PDF FormatRequires Adobe Acrobat Reader