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Table 8.6d

Immunosuppression Use for Maintenance by Regimen

Prior to Discharge, 1999 to 2008

Recipients with Kidney-Pancreas Transplants

  Transplant Year
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Functioning Graft at Discharge 907 888 861 881 847 864 884 905 840 820
With Immunosuppression Info 907 886 861 881 844 851 879 891 831 815
CyA 0.0% 0.1% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0%
Tac 0.7% 0.9% 1.4% 2.3% 1.1% 3.4% 0.8% 1.1% 1.1% 0.6%
--- + MMF/MPA 0.0% 0.0% 0.0% 0.0% 1.1% 2.0% 1.0% 0.4% 0.0% 0.1%
CyA + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.4% 0.2% 0.7% 0.1% 0.4% 0.5%
Tac + MMF/MPA 0.6% 1.1% 0.6% 1.1% 4.0% 6.7% 14.8% 21.1% 24.2% 21.7%
Tac + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.0% 0.0%
--- + Siro/Evero 0.0% 0.0% 0.1% 0.0% 0.0% 0.1% 0.0% 0.0% 0.1% 0.2%
CyA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 1.3% 2.8% 2.8% 3.1% 2.3% 3.2%
Tac + Siro/Evero 0.0% 0.3% 1.6% 4.7% 3.6% 3.8% 6.1% 2.2% 1.2% 0.1%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 2.4% 4.5% 0.2% 0.2% 0.2% 0.0%
CyA + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.3% 0.2% 0.0% 0.0%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 1.5% 1.8% 2.1% 0.9% 1.8% 4.6% 4.5% 2.6%
--- + Steroids 2.2% 1.1% 0.1% 0.0% 1.7% 0.8% 2.2% 0.0% 0.1% 0.0%
CyA + Steroids 0.3% 0.5% 0.3% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + Steroids 2.4% 1.7% 2.3% 1.8% 2.5% 1.5% 2.5% 3.0% 1.3% 2.2%
--- + MMF/MPA + Steroids 1.0% 0.1% 0.8% 0.5% 0.8% 1.3% 0.5% 0.7% 0.7% 0.9%
CyA + MMF/MPA + Steroids 19.4% 12.2% 8.5% 6.9% 5.0% 1.4% 1.8% 1.6% 1.2% 0.5%
Tac + MMF/MPA + Steroids 65.4% 64.6% 61.7% 66.2% 62.4% 64.7% 59.8% 53.6% 59.2% 64.5%
--- + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0%
CyA + OtherAntimet + Steroids 0.1% 0.3% 0.1% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0%
Tac + OtherAntimet + Steroids 1.1% 1.0% 0.1% 0.5% 0.7% 0.2% 0.0% 0.6% 0.4% 0.0%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.2% 0.2% 0.4% 0.0% 0.0% 0.1% 0.1%
CyA + Siro/Evero + Steroids 0.0% 2.6% 1.6% 0.6% 1.8% 0.9% 0.9% 0.7% 0.4% 0.2%
Tac + Siro/Evero + Steroids 0.7% 6.8% 11.0% 7.3% 4.9% 2.2% 2.5% 4.4% 1.3% 1.2%
Other Regimen 6.2% 6.7% 8.1% 5.9% 4.1% 1.8% 1.0% 2.0% 1.3% 1.2%


Source: OPTN/SRTR Data as of May 4, 2009.

Percentages in each column sum to 100 percent.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.



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