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Table 7.7

Patients and Annual Death Rates Per 1,000 Patient-Years at Risk, 1999 to 2007

Rates for Recipients during First Year after Pancreas After Kidney (PAK) Transplantation

Level of HLA Mismatch (Total) Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007
Total   Patients 218 302 302 374 344 419 342 292 258
Deaths 11 13 13 16 17 17 8 9 7
Rate 52.1 44.1 43.8 43.9 50.7 41.4 23.8 31.5 27.7
A Locus Mismatch 0 Patients 52 53 39 67 55 63 46 33 22
Deaths 4 1 1 5 4 5 1 1 0
Rate 80.8 19.0 25.8 79.6 75.9 83.4 22.2 30.9 0.0
1 Patients 105 138 147 183 168 195 163 134 132
Deaths 4 5 7 6 6 3 2 4 3
Rate 39.3 36.9 48.6 33.4 36.4 15.4 12.4 30.5 23.1
2 Patients 61 111 116 124 121 161 133 125 104
Deaths 3 7 5 5 7 9 5 4 4
Rate 50.3 65.5 43.9 41.0 59.4 57.6 38.7 32.7 39.7
Unknown Patients 0 0 0 0 0 0 0 0 0
Deaths 0 0 0 0 0 0 0 0 0
Rate 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
B Locus Mismatch 0 Patients 22 24 24 34 20 32 18 20 8
Deaths 1 2 1 4 3 3 1 1 0
Rate 47.5 88.2 43.1 131.2 165.7 100.3 58.5 51.6 *
1 Patients 95 125 124 130 144 151 125 102 84
Deaths 6 3 4 5 6 5 3 3 1
Rate 65.6 24.1 32.5 39.4 42.7 33.5 24.3 30.1 12.0
2 Patients 101 153 154 210 180 236 199 170 166
Deaths 4 8 8 7 8 9 4 5 6
Rate 40.6 54.0 53.2 33.8 45.3 39.0 20.4 30.0 37.2
Unknown Patients - - - - - - - - -
Deaths - - - - - - - - -
Rate - - - - - - - - -
DR Locus Mismatch 0 Patients 31 44 38 42 41 49 38 32 22
Deaths 2 1 0 3 2 2 2 2 0
Rate 67.0 23.2 0.0 76.5 50.4 41.8 54.5 65.5 0.0
1 Patients 123 151 150 185 166 211 151 120 116
Deaths 6 6 6 7 9 10 3 1 3
Rate 50.7 40.6 41.0 38.7 55.5 48.5 20.2 8.4 26.4
2 Patients 64 107 113 146 137 159 153 140 120
Deaths 3 6 6 6 6 5 3 6 4
Rate 47.8 57.7 53.5 41.8 45.0 32.0 19.9 44.0 34.1
Unknown Patients - - 1 1 - - - - -
Deaths - - 1 0 - - - - -
Rate - - * * - - - - -
Total Mismatch 0 Patients 6 3 6 12 7 11 5 6 4
Deaths 0 0 0 3 1 2 1 1 0
Rate * * * 326.1 * 202.8 * * *
1 Patients 11 15 8 8 10 12 10 8 4
Deaths 1 1 0 0 2 1 0 0 0
Rate 99.3 71.0 * * 222.2 90.4 0.0 * *
2 Patients 31 41 35 31 36 43 20 16 9
Deaths 2 2 1 1 1 1 1 1 0
Rate 67.7 49.8 29.2 33.0 28.4 23.3 51.0 66.0 *
3 Patients 53 56 56 82 65 74 79 54 43
Deaths 4 0 1 5 3 2 0 0 0
Rate 78.5 0.0 18.1 63.8 47.5 27.4 0.0 0.0 0.0
4 Patients 57 81 78 100 99 104 77 67 70
Deaths 2 3 5 2 4 2 1 2 1
Rate 36.0 37.6 65.6 20.1 40.9 19.5 13.1 30.6 14.4
5 Patients 45 69 83 102 81 117 92 90 87
Deaths 1 3 4 1 2 7 4 2 5
Rate 22.7 44.3 48.9 9.8 24.8 61.1 44.9 22.6 60.1
6 Patients 15 37 35 38 46 58 59 51 41
Deaths 1 4 1 4 4 2 1 3 1
Rate 67.5 116.8 28.8 110.5 92.7 35.5 17.2 60.7 24.9
Unknown Patients - - 1 1 - - - - -
Deaths - - 1 0 - - - - -
Rate - - * * - - - - -


Source: OPTN/SRTR Data as of May 4, 2009.

(-) = None in category.

(*) = For cohorts with fewer than 10 patients, rates are imprecise and are not reported.

Multi-organ transplants are excluded.

Includes patients transplanted during the year and having reported data one-year after transplant.

Time at risk covers the period from transplant date until the date of death or one-year anniversary of the transplant. See Technical Notes for further details.

Mismatches are calculated without taking into account HLA from kidney donor.



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