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Table 7.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1998 to 2007

Recipients with Pancreas After Kidney (PAK) Transplants

  Year of Transplant
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Transplants 156 220 305 305 375 344 420 343 293 261
Tx with Follow-up Immunosuppression Info 110 167 220 245 272 258 320 255 221 206
Corticosteroids Any in Category 100.0% 100.0% 98.6% 98.8% 94.5% 78.7% 73.8% 74.9% 71.0% 59.2%
Steroids 100.0% 100.0% 98.6% 98.8% 94.5% 78.7% 73.8% 74.9% 71.0% 59.2%
Cyclosporine Any in Category 32.7% 14.4% 16.4% 15.1% 15.4% 11.2% 8.1% 6.7% 6.8% 5.8%
Sandimmmune 5.5% 2.4% 3.2% 0.8% 1.1% 0.0% 0.3% 0.0% 0.5% 0.5%
Neoral 27.3% 12.0% 12.3% 12.7% 12.1% 9.3% 5.0% 6.3% 6.3% 5.3%
Gengraf 0.0% 0.0% 0.9% 0.8% 2.2% 1.6% 2.8% 0.4% 0.0% 0.0%
Eon 0.0% 0.0% 0.0% 0.8% 0.0% 0.4% 0.0% 0.0% 0.0% 0.0%
Tacrolimus Any in Category 76.4% 91.0% 91.8% 91.8% 87.1% 82.9% 87.2% 92.5% 91.9% 92.7%
Tacrolimus 76.4% 91.0% 91.8% 91.8% 87.1% 82.9% 87.2% 92.5% 91.9% 92.7%
Antimetabolites Any in Category 99.1% 95.2% 84.5% 80.4% 80.5% 84.9% 82.5% 90.6% 87.3% 90.3%
Mycophenolate Mofetil 89.1% 86.2% 78.6% 78.0% 78.3% 81.0% 79.4% 84.3% 75.6% 75.7%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 2.2% 4.3% 8.6% 12.1%
Azathioprine 10.0% 9.0% 5.9% 2.4% 2.2% 3.5% 0.3% 2.0% 1.8% 1.0%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.6% 0.0% 1.4% 1.5%
Cytoxan 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.9% 7.2% 24.5% 30.6% 31.6% 27.5% 25.6% 19.2% 17.2% 18.9%
Sirolimus 0.9% 7.2% 24.5% 30.6% 31.6% 27.5% 25.6% 19.2% 17.2% 18.9%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 4, 2009.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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