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Table 7.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1999 to 2008

Recipients with Pancreas After Kidney (PAK) Transplants

  Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Functioning Graft at Discharge 206 278 287 336 315 380 306 255 240 193
With Immunosuppression Info 203 277 286 335 312 375 303 249 230 192
Corticosteroids Any in Category 90.1% 95.7% 93.4% 89.9% 80.8% 74.7% 66.7% 63.9% 57.8% 59.9%
Steroids 90.1% 95.7% 93.4% 89.9% 80.8% 74.7% 66.7% 63.9% 57.8% 59.9%
Cyclosporine Any in Category 14.3% 13.7% 9.8% 11.3% 8.3% 8.3% 6.6% 5.6% 4.8% 3.6%
Sandimmmune 2.5% 2.2% 0.7% 0.6% 0.3% 0.5% 0.3% 0.0% 1.7% 0.0%
Neoral 11.3% 11.6% 8.0% 9.0% 6.1% 5.6% 5.9% 5.2% 3.0% 3.1%
Gengraf 0.5% 0.0% 1.0% 1.8% 1.9% 2.1% 0.3% 0.4% 0.0% 0.5%
Tacrolimus Any in Category 83.3% 85.2% 90.6% 86.3% 80.8% 79.7% 85.5% 92.0% 93.0% 92.7%
Tacrolimus 83.3% 85.2% 90.6% 86.3% 80.8% 79.7% 85.5% 92.0% 93.0% 92.7%
Antimetabolites Any in Category 85.2% 82.3% 75.5% 74.3% 85.6% 80.3% 83.8% 84.3% 94.3% 93.8%
Mycophenolate Mofetil 81.8% 80.5% 74.1% 74.0% 84.9% 78.9% 79.5% 74.3% 83.9% 79.2%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 1.1% 3.3% 9.6% 9.1% 13.0%
Azathioprine 3.4% 1.8% 1.4% 0.3% 0.6% 0.3% 1.0% 0.4% 1.3% 1.0%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.5%
mTOR Inhibitors Any in Category 1.5% 8.3% 22.0% 19.4% 14.7% 16.3% 13.9% 15.7% 7.8% 7.8%
Sirolimus 1.5% 8.3% 22.0% 19.4% 14.7% 16.3% 13.9% 15.7% 7.8% 7.8%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 4, 2009.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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