Table 7.6d

Immunosuppression Use for Maintenance by Regimen

Prior to Discharge, 1999 to 2008

Recipients with Pancreas After Kidney (PAK) Transplants

	Transplant Year
	1999	2000	2001	2002	2003	2004	2005	2006	2007	2008
Functioning Graft at Discharge	206	278	287	336	315	380	306	255	240	193
With Immunosuppression Info	203	277	286	335	312	375	303	249	230	192
CyA	0.0%	0.0%	0.3%	0.3%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%
Tac	6.9%	4.0%	3.8%	4.8%	1.3%	2.7%	3.0%	2.4%	2.6%	1.0%
--- + MMF/MPA	0.0%	0.0%	0.0%	0.0%	5.8%	5.1%	2.0%	0.0%	0.9%	0.5%
CyA + MMF/MPA	0.5%	0.0%	0.7%	0.3%	1.0%	1.3%	2.0%	0.8%	0.9%	0.0%
Tac + MMF/MPA	0.5%	0.0%	0.3%	0.9%	6.4%	8.0%	17.8%	23.3%	29.6%	32.3%
Tac + OtherAntimet	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.3%	0.0%	0.0%	0.0%
Tac + MMF/MPA + OtherAntimet	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.5%
--- + Siro/Evero	0.0%	0.0%	0.0%	0.0%	0.0%	0.5%	0.3%	0.0%	0.0%	0.5%
CyA + Siro/Evero	0.0%	0.0%	0.0%	0.0%	0.0%	1.1%	1.0%	2.4%	0.4%	1.6%
Tac + Siro/Evero	0.0%	0.0%	1.0%	2.4%	2.2%	4.0%	4.3%	2.4%	0.0%	0.0%
--- + MMF/MPA + Siro/Evero	0.0%	0.0%	0.0%	0.0%	0.3%	1.6%	0.3%	0.4%	0.4%	0.5%
CyA + MMF/MPA + Siro/Evero	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.3%	0.0%	0.0%	0.0%
Tac + MMF/MPA + Siro/Evero	0.0%	0.0%	0.0%	0.3%	1.6%	0.8%	1.7%	3.6%	7.0%	3.1%
--- + Steroids	2.0%	1.8%	0.3%	0.3%	1.0%	2.7%	3.3%	0.0%	0.0%	0.5%
CyA + Steroids	0.5%	0.0%	0.0%	0.3%	0.3%	0.5%	0.0%	0.4%	0.4%	0.0%
Tac + Steroids	2.5%	4.3%	1.0%	2.4%	1.3%	2.1%	0.3%	0.8%	1.7%	1.0%
--- + MMF/MPA + Steroids	1.0%	0.0%	0.3%	1.5%	1.6%	1.6%	0.3%	0.4%	1.3%	2.1%
CyA + MMF/MPA + Steroids	10.3%	10.8%	5.6%	7.2%	5.1%	3.5%	2.3%	2.0%	1.7%	1.6%
Tac + MMF/MPA + Steroids	68.5%	67.5%	62.6%	60.6%	59.9%	55.2%	53.8%	53.0%	50.9%	51.0%
CyA + OtherAntimet + Steroids	0.0%	0.0%	0.0%	0.0%	0.3%	0.0%	0.0%	0.0%	0.4%	0.0%
Tac + OtherAntimet + Steroids	2.0%	1.8%	0.7%	0.3%	0.3%	0.3%	0.7%	0.0%	0.4%	1.0%
--- + Siro/Evero + Steroids	0.0%	0.0%	0.0%	0.3%	0.3%	0.3%	0.3%	0.4%	0.0%	0.0%
CyA + Siro/Evero + Steroids	0.5%	1.8%	1.4%	2.1%	1.3%	0.8%	0.7%	0.0%	0.0%	0.0%
Tac + Siro/Evero + Steroids	1.0%	5.4%	15.7%	11.3%	6.1%	4.5%	2.6%	6.0%	0.0%	1.0%
Other Regimen	3.9%	2.5%	5.9%	4.8%	3.8%	3.5%	2.6%	1.6%	1.3%	1.6%

Source: OPTN/SRTR Data as of May 4, 2009.

Percentages in each column sum to 100 percent.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.