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Table 15.6

Steroid Avoidance Rate at Discharge, 1998 to 2007

Recipients of Heart Transplants

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Total Patients 2,040 1,849 1,909 1,914 1,905 1,817 1,779 1,849 1,919 1,949
Steroids Avoided 79 80 102 54 56 134 140 120 151 219
Rate 3.9% 4.3% 5.3% 2.8% 2.9% 7.4% 7.9% 6.5% 7.9% 11.2%
CyA Patients 86 216 89 37 47 34 13 14 27 19
Steroids Avoided 6 10 13 6 1 2 2 2 3 1
Rate 7.0% 4.6% 14.6% 16.2% 2.1% 5.9% 15.4% 14.3% 11.1% 5.3%
Tac Patients 38 43 41 68 75 60 38 44 46 57
Steroids Avoided 2 2 2 5 2 7 3 7 11 13
Rate 5.3% 4.7% 4.9% 7.4% 2.7% 11.7% 7.9% 15.9% 23.9% 22.8%
CyA+MMF Patients 693 748 1,078 1,011 825 805 739 615 595 523
Steroids Avoided 21 18 37 18 15 37 34 30 37 46
Rate 3.0% 2.4% 3.4% 1.8% 1.8% 4.6% 4.6% 4.9% 6.2% 8.8%
Tac+MMF Patients 120 151 161 371 460 540 688 893 1,001 1,155
Steroids Avoided 6 1 5 7 16 48 47 48 71 138
Rate 5.0% 0.7% 3.1% 1.9% 3.5% 8.9% 6.8% 5.4% 7.1% 11.9%
CyA+Aza Patients 821 478 301 204 136 92 83 48 42 28
Steroids Avoided 29 14 21 9 11 10 14 7 3 3
Rate 3.5% 2.9% 7.0% 4.4% 8.1% 10.9% 16.9% 14.6% 7.1% 10.7%
Tac+Aza Patients 49 36 39 25 25 24 22 20 26 20
Steroids Avoided 1 3 1 1 2 2 4 4 1 4
Rate 2.0% 8.3% 2.6% 4.0% 8.0% 8.3% 18.2% 20.0% 3.8% 20.0%
CyA+Siro Patients 1 11 12 3 18 38 2 1 2 -
Steroids Avoided 0 0 1 0 1 1 0 0 0 -
Rate 0.0% 0.0% 8.3% 0.0% 5.6% 2.6% 0.0% 0.0% 0.0% -
Tac+Siro Patients - 2 17 39 108 32 15 21 19 6
Steroids Avoided - 0 0 0 3 1 2 6 8 5
Rate - 0.0% 0.0% 0.0% 2.8% 3.1% 13.3% 28.6% 42.1% 83.3%
Siro+MMF Patients - - - 4 7 18 19 16 22 5
Steroids Avoided - - - 0 0 1 2 1 1 0
Rate - - - 0.0% 0.0% 5.6% 10.5% 6.3% 4.5% 0.0%
Other Regimen Patients 232 164 171 152 204 174 160 177 139 136
Steroids Avoided 14 32 22 8 5 25 32 15 16 9
Rate 6.0% 19.5% 12.9% 5.3% 2.5% 14.4% 20.0% 8.5% 11.5% 6.6%


Source: OPTN/SRTR Data as of May 1, 2008.

Includes patients receiving first transplants of any organ with a functioning graft at discharge and any immunosuppressive drug use recorded at discharge.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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