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Table 15.6

Steroid Avoidance Rate at Discharge, 1999 to 2008

Recipients of Heart Transplants

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 1,849 1,909 1,914 1,905 1,817 1,779 1,849 1,919 1,963 1,951
Steroids Avoided 80 102 54 56 134 140 120 151 218 244
Rate 4.3% 5.3% 2.8% 2.9% 7.4% 7.9% 6.5% 7.9% 11.1% 12.5%
CyA Patients 216 89 37 47 34 13 14 27 19 13
Steroids Avoided 10 13 6 1 2 2 2 3 1 1
Rate 4.6% 14.6% 16.2% 2.1% 5.9% 15.4% 14.3% 11.1% 5.3% 7.7%
Tac Patients 43 41 68 75 60 38 44 46 58 66
Steroids Avoided 2 2 5 2 7 3 7 11 13 21
Rate 4.7% 4.9% 7.4% 2.7% 11.7% 7.9% 15.9% 23.9% 22.4% 31.8%
CyA+MMF Patients 748 1,078 1,011 825 805 739 615 595 525 407
Steroids Avoided 18 37 18 15 37 34 30 37 47 38
Rate 2.4% 3.4% 1.8% 1.8% 4.6% 4.6% 4.9% 6.2% 9.0% 9.3%
Tac+MMF Patients 151 161 371 460 540 688 893 1,001 1,166 1,285
Steroids Avoided 1 5 7 16 48 47 48 71 136 165
Rate 0.7% 3.1% 1.9% 3.5% 8.9% 6.8% 5.4% 7.1% 11.7% 12.8%
CyA+Aza Patients 478 301 204 136 92 83 48 42 29 15
Steroids Avoided 14 21 9 11 10 14 7 3 3 4
Rate 2.9% 7.0% 4.4% 8.1% 10.9% 16.9% 14.6% 7.1% 10.3% 26.7%
Tac+Aza Patients 36 39 25 25 24 22 20 26 20 27
Steroids Avoided 3 1 1 2 2 4 4 1 4 1
Rate 8.3% 2.6% 4.0% 8.0% 8.3% 18.2% 20.0% 3.8% 20.0% 3.7%
CyA+Siro Patients 11 12 3 18 38 2 1 2 - 2
Steroids Avoided 0 1 0 1 1 0 0 0 - 0
Rate 0.0% 8.3% 0.0% 5.6% 2.6% 0.0% 0.0% 0.0% - 0.0%
Tac+Siro Patients 2 17 39 108 32 15 21 19 6 5
Steroids Avoided 0 0 0 3 1 2 6 8 5 5
Rate 0.0% 0.0% 0.0% 2.8% 3.1% 13.3% 28.6% 42.1% 83.3% 100.0%
Siro+MMF Patients - - 4 7 18 19 16 22 5 4
Steroids Avoided - - 0 0 1 2 1 1 0 0
Rate - - 0.0% 0.0% 5.6% 10.5% 6.3% 4.5% 0.0% 0.0%
Other Regimen Patients 164 171 152 204 174 160 177 139 135 127
Steroids Avoided 32 22 8 5 25 32 15 16 9 9
Rate 19.5% 12.9% 5.3% 2.5% 14.4% 20.0% 8.5% 11.5% 6.7% 7.1%


Source: OPTN/SRTR Data as of May 4, 2009.

Includes patients receiving first transplants of any organ with a functioning graft at discharge and any immunosuppressive drug use recorded at discharge.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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