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Table 15.5b

Steroid Avoidance Rate at Discharge, 1999 to 2008

Recipients of Living Donor Livers

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 193 328 452 308 282 292 289 260 244 225
Steroids Avoided 13 30 40 25 63 64 69 73 71 48
Rate 6.7% 9.1% 8.8% 8.1% 22.3% 21.9% 23.9% 28.1% 29.1% 21.3%
CyA Patients 14 17 16 6 9 - 1 1 1 1
Steroids Avoided 4 1 8 1 1 - 0 0 1 1
Rate 28.6% 5.9% 50.0% 16.7% 11.1% - 0.0% 0.0% 100.0% 100.0%
Tac Patients 96 126 156 123 101 105 103 105 73 52
Steroids Avoided 4 7 11 18 27 35 36 31 11 4
Rate 4.2% 5.6% 7.1% 14.6% 26.7% 33.3% 35.0% 29.5% 15.1% 7.7%
CyA+MMF Patients 14 18 24 22 18 18 9 4 7 6
Steroids Avoided 1 0 0 2 2 1 2 2 2 1
Rate 7.1% 0.0% 0.0% 9.1% 11.1% 5.6% 22.2% 50.0% 28.6% 16.7%
Tac+MMF Patients 50 111 173 118 136 142 152 142 142 153
Steroids Avoided 3 5 2 3 28 24 23 39 51 40
Rate 6.0% 4.5% 1.2% 2.5% 20.6% 16.9% 15.1% 27.5% 35.9% 26.1%
CyA+Aza Patients 3 3 2 4 3 2 2 - 3 1
Steroids Avoided 0 0 0 0 1 0 0 - 0 0
Rate 0.0% 0.0% 0.0% 0.0% 33.3% 0.0% 0.0% - 0.0% 0.0%
Tac+Aza Patients 4 2 - 3 - - 1 - 2 1
Steroids Avoided 0 0 - 0 - - 1 - 1 0
Rate 0.0% 0.0% - 0.0% - - 100.0% - 50.0% 0.0%
CyA+Siro Patients - 7 6 2 - 1 - - - -
Steroids Avoided - 4 3 0 - 0 - - - -
Rate - 57.1% 50.0% 0.0% - 0.0% - - - -
Tac+Siro Patients - 20 36 11 1 5 1 2 3 -
Steroids Avoided - 8 11 0 0 1 0 0 0 -
Rate - 40.0% 30.6% 0.0% 0.0% 20.0% 0.0% 0.0% 0.0% -
Siro+MMF Patients - 1 5 2 1 1 1 - 2 -
Steroids Avoided - 0 0 0 0 0 0 - 0 -
Rate - 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% - 0.0% -
Other Regimen Patients 12 23 34 17 13 18 19 6 11 11
Steroids Avoided 1 5 5 1 4 3 7 1 5 2
Rate 8.3% 21.7% 14.7% 5.9% 30.8% 16.7% 36.8% 16.7% 45.5% 18.2%


Source: OPTN/SRTR Data as of May 4, 2009.

Includes patients receiving first transplants of any organ with a functioning graft at discharge and any immunosuppressive drug use recorded at discharge.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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