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Table 15.5a

Steroid Avoidance Rate at Discharge, 1999 to 2008

Recipients of Deceased Donor Livers

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 3,423 3,619 3,748 4,060 4,435 4,884 5,022 5,318 5,268 5,162
Steroids Avoided 243 294 369 405 771 956 1,062 1,150 1,272 1,032
Rate 7.1% 8.1% 9.8% 10.0% 17.4% 19.6% 21.1% 21.6% 24.1% 20.0%
CyA Patients 372 226 117 97 76 58 65 34 43 37
Steroids Avoided 36 6 18 11 20 10 12 6 5 10
Rate 9.7% 2.7% 15.4% 11.3% 26.3% 17.2% 18.5% 17.6% 11.6% 27.0%
Tac Patients 1,381 1,194 1,338 1,646 1,639 1,760 1,691 1,369 1,225 1,001
Steroids Avoided 80 52 129 195 331 485 504 282 246 196
Rate 5.8% 4.4% 9.6% 11.8% 20.2% 27.6% 29.8% 20.6% 20.1% 19.6%
CyA+MMF Patients 315 258 212 186 179 194 188 218 227 232
Steroids Avoided 9 11 7 8 19 40 28 52 69 48
Rate 2.9% 4.3% 3.3% 4.3% 10.6% 20.6% 14.9% 23.9% 30.4% 20.7%
Tac+MMF Patients 882 1,204 1,433 1,595 2,050 2,334 2,703 3,292 3,432 3,547
Steroids Avoided 56 95 107 124 284 303 433 687 827 708
Rate 6.3% 7.9% 7.5% 7.8% 13.9% 13.0% 16.0% 20.9% 24.1% 20.0%
CyA+Aza Patients 147 109 51 56 24 52 12 5 4 6
Steroids Avoided 12 1 0 6 22 26 0 0 0 0
Rate 8.2% 0.9% 0.0% 10.7% 91.7% 50.0% 0.0% 0.0% 0.0% 0.0%
Tac+Aza Patients 100 76 65 88 100 47 21 11 19 6
Steroids Avoided 5 3 4 2 13 19 17 5 9 0
Rate 5.0% 3.9% 6.2% 2.3% 13.0% 40.4% 81.0% 45.5% 47.4% 0.0%
CyA+Siro Patients 3 36 25 25 23 23 31 42 34 28
Steroids Avoided 0 23 16 1 0 2 13 39 31 17
Rate 0.0% 63.9% 64.0% 4.0% 0.0% 8.7% 41.9% 92.9% 91.2% 60.7%
Tac+Siro Patients 4 194 197 107 54 85 50 65 22 21
Steroids Avoided 0 34 33 15 8 22 5 10 5 7
Rate 0.0% 17.5% 16.8% 14.0% 14.8% 25.9% 10.0% 15.4% 22.7% 33.3%
Siro+MMF Patients 2 28 48 46 43 42 45 43 34 37
Steroids Avoided 0 1 0 3 8 5 6 12 9 15
Rate 0.0% 3.6% 0.0% 6.5% 18.6% 11.9% 13.3% 27.9% 26.5% 40.5%
Other Regimen Patients 217 294 262 214 247 289 216 239 228 247
Steroids Avoided 45 68 55 40 66 44 44 57 71 31
Rate 20.7% 23.1% 21.0% 18.7% 26.7% 15.2% 20.4% 23.8% 31.1% 12.6%


Source: OPTN/SRTR Data as of May 4, 2009.

Includes patients receiving first transplants of any organ with a functioning graft at discharge and any immunosuppressive drug use recorded at discharge.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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