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Table 15.4b

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2006

Recipients of Living Donor Kidneys

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006
Total Patients 3,256 3,860 4,089 4,103 3,892 3,549 2,625 2,259
Steroids Withdrawn 179 270 382 527 567 570 468 359
Rate 5.5% 7.0% 9.3% 12.8% 14.6% 16.1% 17.8% 15.9%
CyA Patients 197 141 93 63 75 77 14 12
Steroids Withdrawn 11 10 12 3 4 6 2 1
Rate 5.6% 7.1% 12.9% 4.8% 5.3% 7.8% 14.3% 8.3%
Tac Patients 92 143 150 124 116 116 57 53
Steroids Withdrawn 13 21 23 16 18 24 13 4
Rate 14.1% 14.7% 15.3% 12.9% 15.5% 20.7% 22.8% 7.5%
CyA+MMF Patients 1,662 1,638 1,355 1,080 824 713 360 180
Steroids Withdrawn 69 57 73 74 54 65 34 23
Rate 4.2% 3.5% 5.4% 6.9% 6.6% 9.1% 9.4% 12.8%
Tac+MMF Patients 793 1,126 1,613 2,044 2,122 2,051 1,785 1,595
Steroids Withdrawn 51 96 167 266 325 341 301 282
Rate 6.4% 8.5% 10.4% 13.0% 15.3% 16.6% 16.9% 17.7%
CyA+Aza Patients 219 163 126 44 19 10 4 5
Steroids Withdrawn 8 7 4 2 0 0 0 0
Rate 3.7% 4.3% 3.2% 4.5% 0.0% 0.0% 0.0% 0.0%
Tac+Aza Patients 50 51 65 72 62 34 5 7
Steroids Withdrawn 9 13 17 17 4 5 1 0
Rate 18.0% 25.5% 26.2% 23.6% 6.5% 14.7% 20.0% 0.0%
CyA+Siro Patients 47 227 149 101 99 40 38 18
Steroids Withdrawn 3 26 13 34 32 3 6 1
Rate 6.4% 11.5% 8.7% 33.7% 32.3% 7.5% 15.8% 5.6%
Tac+Siro Patients 4 159 278 258 223 156 106 166
Steroids Withdrawn 1 14 47 58 53 30 19 20
Rate 25.0% 8.8% 16.9% 22.5% 23.8% 19.2% 17.9% 12.0%
Siro+MMF Patients 1 29 89 115 105 73 80 55
Steroids Withdrawn 0 1 2 23 20 12 25 10
Rate 0.0% 3.4% 2.2% 20.0% 19.0% 16.4% 31.3% 18.2%
Other Regimen Patients 191 183 171 202 247 279 176 168
Steroids Withdrawn 14 25 24 34 57 84 67 18
Rate 7.3% 13.7% 14.0% 16.8% 23.1% 30.1% 38.1% 10.7%


Source: OPTN/SRTR Data as of May 4, 2009.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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