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Table 15.4b

Steroid Avoidance Rate at Discharge, 1999 to 2008

Recipients of Living Donor Kidneys

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 4,075 4,726 5,188 5,354 5,508 5,682 5,553 5,514 5,167 5,139
Steroids Avoided 118 262 464 630 1,015 1,607 1,815 2,087 2,119 2,087
Rate 2.9% 5.5% 8.9% 11.8% 18.4% 28.3% 32.7% 37.8% 41.0% 40.6%
CyA Patients 235 167 123 80 104 122 26 28 21 6
Steroids Avoided 1 4 8 4 10 20 6 10 3 2
Rate 0.4% 2.4% 6.5% 5.0% 9.6% 16.4% 23.1% 35.7% 14.3% 33.3%
Tac Patients 120 203 220 233 191 197 137 191 186 166
Steroids Avoided 5 30 46 87 64 68 57 112 97 92
Rate 4.2% 14.8% 20.9% 37.3% 33.5% 34.5% 41.6% 58.6% 52.2% 55.4%
CyA+MMF Patients 2,047 1,924 1,640 1,303 1,121 954 710 502 412 318
Steroids Avoided 36 64 66 45 111 123 112 117 116 61
Rate 1.8% 3.3% 4.0% 3.5% 9.9% 12.9% 15.8% 23.3% 28.2% 19.2%
Tac+MMF Patients 1,019 1,396 1,977 2,594 2,881 3,339 3,843 3,971 3,981 4,154
Steroids Avoided 48 73 132 261 477 1,006 1,336 1,575 1,700 1,710
Rate 4.7% 5.2% 6.7% 10.1% 16.6% 30.1% 34.8% 39.7% 42.7% 41.2%
CyA+Aza Patients 270 186 145 51 20 14 5 6 8 3
Steroids Avoided 7 3 2 0 1 1 1 1 7 2
Rate 2.6% 1.6% 1.4% 0.0% 5.0% 7.1% 20.0% 16.7% 87.5% 66.7%
Tac+Aza Patients 61 60 84 82 70 41 9 17 14 13
Steroids Avoided 3 5 11 6 7 6 3 7 2 3
Rate 4.9% 8.3% 13.1% 7.3% 10.0% 14.6% 33.3% 41.2% 14.3% 23.1%
CyA+Siro Patients 60 260 170 142 168 129 148 135 90 89
Steroids Avoided 0 1 5 30 60 81 103 112 67 62
Rate 0.0% 0.4% 2.9% 21.1% 35.7% 62.8% 69.6% 83.0% 74.4% 69.7%
Tac+Siro Patients 6 217 429 382 370 324 210 253 67 32
Steroids Avoided 0 22 103 94 115 145 78 65 29 24
Rate 0.0% 10.1% 24.0% 24.6% 31.1% 44.8% 37.1% 25.7% 43.3% 75.0%
Siro+MMF Patients 1 45 109 152 154 109 132 85 53 61
Steroids Avoided 0 12 8 6 22 26 20 16 10 14
Rate 0.0% 26.7% 7.3% 3.9% 14.3% 23.9% 15.2% 18.8% 18.9% 23.0%
Other Regimen Patients 256 268 291 335 429 453 333 326 335 297
Steroids Avoided 18 48 83 97 148 131 99 72 88 117
Rate 7.0% 17.9% 28.5% 29.0% 34.5% 28.9% 29.7% 22.1% 26.3% 39.4%


Source: OPTN/SRTR Data as of May 4, 2009.

Includes patients receiving first transplants of any organ with a functioning graft at discharge and any immunosuppressive drug use recorded at discharge.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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