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Table 15.4a

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2006

Recipients of Deceased Donor Kidneys

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006
Total Patients 4,901 4,994 5,192 5,302 5,035 4,971 3,957 3,581
Steroids Withdrawn 271 279 427 511 540 634 628 465
Rate 5.5% 5.6% 8.2% 9.6% 10.7% 12.8% 15.9% 13.0%
CyA Patients 269 170 77 71 77 80 23 19
Steroids Withdrawn 11 4 8 12 9 3 1 1
Rate 4.1% 2.4% 10.4% 16.9% 11.7% 3.8% 4.3% 5.3%
Tac Patients 136 157 207 195 117 159 139 80
Steroids Withdrawn 14 20 34 33 24 49 36 8
Rate 10.3% 12.7% 16.4% 16.9% 20.5% 30.8% 25.9% 10.0%
CyA+MMF Patients 2,431 2,031 1,573 1,388 1,097 934 502 332
Steroids Withdrawn 81 57 55 61 90 77 32 18
Rate 3.3% 2.8% 3.5% 4.4% 8.2% 8.2% 6.4% 5.4%
Tac+MMF Patients 1,266 1,565 2,128 2,686 2,833 3,069 2,762 2,589
Steroids Withdrawn 103 124 207 262 283 403 442 371
Rate 8.1% 7.9% 9.7% 9.8% 10.0% 13.1% 16.0% 14.3%
CyA+Aza Patients 286 198 100 44 23 13 6 6
Steroids Withdrawn 19 6 4 1 1 0 0 0
Rate 6.6% 3.0% 4.0% 2.3% 4.3% 0.0% 0.0% 0.0%
Tac+Aza Patients 59 46 73 51 39 23 8 16
Steroids Withdrawn 12 14 9 14 7 1 0 1
Rate 20.3% 30.4% 12.3% 27.5% 17.9% 4.3% 0.0% 6.3%
CyA+Siro Patients 73 248 234 146 139 89 67 64
Steroids Withdrawn 3 9 16 15 11 8 10 1
Rate 4.1% 3.6% 6.8% 10.3% 7.9% 9.0% 14.9% 1.6%
Tac+Siro Patients 8 214 310 209 262 172 97 153
Steroids Withdrawn 0 15 46 37 38 11 12 11
Rate 0.0% 7.0% 14.8% 17.7% 14.5% 6.4% 12.4% 7.2%
Siro+MMF Patients 8 62 173 192 148 119 83 74
Steroids Withdrawn 0 2 10 18 24 21 12 15
Rate 0.0% 3.2% 5.8% 9.4% 16.2% 17.6% 14.5% 20.3%
Other Regimen Patients 365 303 317 320 300 313 270 248
Steroids Withdrawn 28 28 38 58 53 61 83 39
Rate 7.7% 9.2% 12.0% 18.1% 17.7% 19.5% 30.7% 15.7%


Source: OPTN/SRTR Data as of May 4, 2009.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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