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Table 15.4a

Steroid Withdrawal Rate at One Year Following Transplantation, 1999 to 2007

Recipients of Deceased Donor Kidneys

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007
Total Patients 5,364 5,198 5,684 5,744 5,463 5,446 5,359 5,297 5,265
Steroids Withdrawn 206 244 263 438 431 499 693 559 616
Rate 3.8% 4.7% 4.6% 7.6% 7.9% 9.2% 12.9% 10.6% 11.7%
CyA Patients 283 180 83 80 87 91 32 24 23
Steroids Withdrawn 14 20 2 7 6 2 1 1 1
Rate 4.9% 11.1% 2.4% 8.8% 6.9% 2.2% 3.1% 4.2% 4.3%
Tac Patients 149 159 232 213 129 168 195 114 142
Steroids Withdrawn 11 14 30 31 21 44 43 8 12
Rate 7.4% 8.8% 12.9% 14.6% 16.3% 26.2% 22.1% 7.0% 8.5%
CyA+MMF Patients 2,674 2,053 1,714 1,536 1,238 1,008 729 538 412
Steroids Withdrawn 68 51 36 54 72 65 45 25 37
Rate 2.5% 2.5% 2.1% 3.5% 5.8% 6.4% 6.2% 4.6% 9.0%
Tac+MMF Patients 1,374 1,668 2,334 2,863 3,025 3,371 3,734 3,903 4,213
Steroids Withdrawn 73 91 112 225 223 311 478 468 506
Rate 5.3% 5.5% 4.8% 7.9% 7.4% 9.2% 12.8% 12.0% 12.0%
CyA+Aza Patients 311 205 106 51 27 14 7 7 9
Steroids Withdrawn 9 4 2 2 1 0 0 0 0
Rate 2.9% 2.0% 1.9% 3.9% 3.7% 0.0% 0.0% 0.0% 0.0%
Tac+Aza Patients 67 49 78 56 42 23 12 16 10
Steroids Withdrawn 5 11 7 11 3 1 1 1 0
Rate 7.5% 22.4% 9.0% 19.6% 7.1% 4.3% 8.3% 6.3% 0.0%
CyA+Siro Patients 91 270 251 157 150 108 83 74 56
Steroids Withdrawn 5 7 5 11 8 4 12 1 4
Rate 5.5% 2.6% 2.0% 7.0% 5.3% 3.7% 14.5% 1.4% 7.1%
Tac+Siro Patients 9 236 350 233 285 195 122 174 62
Steroids Withdrawn 0 15 32 32 23 5 15 13 2
Rate 0.0% 6.4% 9.1% 13.7% 8.1% 2.6% 12.3% 7.5% 3.2%
Siro+MMF Patients 8 68 188 213 154 133 111 86 53
Steroids Withdrawn 0 2 7 9 18 14 8 6 7
Rate 0.0% 2.9% 3.7% 4.2% 11.7% 10.5% 7.2% 7.0% 13.2%
Other Regimen Patients 398 310 348 342 326 335 334 361 285
Steroids Withdrawn 21 29 30 56 56 53 90 36 47
Rate 5.3% 9.4% 8.6% 16.4% 17.2% 15.8% 26.9% 10.0% 16.5%


Source: OPTN/SRTR Data as of May 4, 2009.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioning graft and maintenance drug use one year after transplantation.

Transplants prior to year 1999 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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