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Table 15.4a

Steroid Avoidance Rate at Discharge, 1999 to 2008

Recipients of Deceased Donor Kidneys

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Patients 6,486 6,403 6,712 6,973 7,129 7,600 8,077 8,690 8,759 8,809
Steroids Avoided 166 256 341 513 979 1,521 2,106 2,724 2,824 2,853
Rate 2.6% 4.0% 5.1% 7.4% 13.7% 20.0% 26.1% 31.3% 32.2% 32.4%
CyA Patients 351 214 104 91 105 114 51 39 35 14
Steroids Avoided 16 4 2 2 11 12 10 11 8 2
Rate 4.6% 1.9% 1.9% 2.2% 10.5% 10.5% 19.6% 28.2% 22.9% 14.3%
Tac Patients 197 234 341 394 221 277 358 288 268 268
Steroids Avoided 11 34 78 154 65 90 133 156 97 115
Rate 5.6% 14.5% 22.9% 39.1% 29.4% 32.5% 37.2% 54.2% 36.2% 42.9%
CyA+MMF Patients 3,164 2,522 1,970 1,773 1,517 1,281 903 787 636 427
Steroids Avoided 31 45 44 43 97 117 77 170 158 59
Rate 1.0% 1.8% 2.2% 2.4% 6.4% 9.1% 8.5% 21.6% 24.8% 13.8%
Tac+MMF Patients 1,642 1,994 2,624 3,335 3,744 4,608 5,662 6,465 7,050 7,364
Steroids Avoided 35 53 75 125 400 909 1,558 2,087 2,331 2,469
Rate 2.1% 2.7% 2.9% 3.7% 10.7% 19.7% 27.5% 32.3% 33.1% 33.5%
CyA+Aza Patients 366 233 123 56 32 14 9 7 10 7
Steroids Avoided 0 1 1 1 2 0 1 0 1 1
Rate 0.0% 0.4% 0.8% 1.8% 6.3% 0.0% 11.1% 0.0% 10.0% 14.3%
Tac+Aza Patients 79 54 84 60 48 26 24 26 17 24
Steroids Avoided 1 1 1 1 1 1 11 9 7 4
Rate 1.3% 1.9% 1.2% 1.7% 2.1% 3.8% 45.8% 34.6% 41.2% 16.7%
CyA+Siro Patients 120 303 294 186 221 211 164 124 124 138
Steroids Avoided 4 2 11 9 55 93 72 41 60 53
Rate 3.3% 0.7% 3.7% 4.8% 24.9% 44.1% 43.9% 33.1% 48.4% 38.4%
Tac+Siro Patients 11 302 452 339 440 331 214 253 113 59
Steroids Avoided 0 30 55 73 117 111 76 63 45 17
Rate 0.0% 9.9% 12.2% 21.5% 26.6% 33.5% 35.5% 24.9% 39.8% 28.8%
Siro+MMF Patients 9 85 257 272 211 207 171 156 80 67
Steroids Avoided 0 5 15 19 35 51 38 60 16 18
Rate 0.0% 5.9% 5.8% 7.0% 16.6% 24.6% 22.2% 38.5% 20.0% 26.9%
Other Regimen Patients 547 462 463 467 590 531 521 545 426 441
Steroids Avoided 68 81 59 86 196 137 130 127 101 115
Rate 12.4% 17.5% 12.7% 18.4% 33.2% 25.8% 25.0% 23.3% 23.7% 26.1%


Source: OPTN/SRTR Data as of May 4, 2009.

Includes patients receiving first transplants of any organ with a functioning graft at discharge and any immunosuppressive drug use recorded at discharge.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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