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Table 14.6

De Novo Posttransplant Solid Malignancy, 1999 to 2008

Kidney Recipients

Malignancies by Type Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Total # of Post-Tx Malignancies 1,046 1,100 1,016 897 825 754 621 477 263 93
Squamous/Basal Cell Carcinoma 569 562 510 470 414 389 287 240 135 48
Melanoma 30 37 26 29 30 21 16 17 12 6
Kaposi Sarcoma 7 10 8 2 5 6 3 5 2 1
Central Nervous System 8 9 12 9 4 5 6 4 2 1
Genito-Urinary (1) 154 163 142 137 122 113 105 67 39 14
Gastro-Intestinal (2) 95 77 71 55 54 53 49 43 19 8
Primary Hepatic Tumor 4 11 9 8 4 10 6 8 9 4
Metastatic Hepatic Tumor 9 13 19 14 12 8 10 8 4 1
Larynx/Bronchi/Lung 75 82 93 73 75 68 68 39 13 2
Breast/Thyroid 43 58 55 48 57 38 35 21 16 5
Leukemia 4 5 9 9 4 9 5 3 1 1
Sarcoma (3) 2 3 5 - 4 3 1 1 2 -
Other 36 55 47 34 25 29 25 16 9 2
Unknown 10 15 10 9 15 2 5 5 - -
Squamous/Basal Cell Carcinoma 54.4% 51.1% 50.2% 52.4% 50.2% 51.6% 46.2% 50.3% 51.3% 51.6%
Melanoma 2.9% 3.4% 2.6% 3.2% 3.6% 2.8% 2.6% 3.6% 4.6% 6.5%
Kaposi Sarcoma 0.7% 0.9% 0.8% 0.2% 0.6% 0.8% 0.5% 1.0% 0.8% 1.1%
Central Nervous System 0.8% 0.8% 1.2% 1.0% 0.5% 0.7% 1.0% 0.8% 0.8% 1.1%
Genito-Urinary (1) 14.7% 14.8% 14.0% 15.3% 14.8% 15.0% 16.9% 14.0% 14.8% 15.1%
Gastro-Intestinal (2) 9.1% 7.0% 7.0% 6.1% 6.5% 7.0% 7.9% 9.0% 7.2% 8.6%
Primary Hepatic Tumor 0.4% 1.0% 0.9% 0.9% 0.5% 1.3% 1.0% 1.7% 3.4% 4.3%
Metastatic Hepatic Tumor 0.9% 1.2% 1.9% 1.6% 1.5% 1.1% 1.6% 1.7% 1.5% 1.1%
Larynx/Bronchi/Lung 7.2% 7.5% 9.2% 8.1% 9.1% 9.0% 11.0% 8.2% 4.9% 2.2%
Breast/Thyroid 4.1% 5.3% 5.4% 5.4% 6.9% 5.0% 5.6% 4.4% 6.1% 5.4%
Leukemia 0.4% 0.5% 0.9% 1.0% 0.5% 1.2% 0.8% 0.6% 0.4% 1.1%
Sarcoma (3) 0.2% 0.3% 0.5% - 0.5% 0.4% 0.2% 0.2% 0.8% -
Other 3.4% 5.0% 4.6% 3.8% 3.0% 3.8% 4.0% 3.4% 3.4% 2.2%
Unknown 1.0% 1.4% 1.0% 1.0% 1.8% 0.3% 0.8% 1.0% - -
Total # of Patients 718 738 717 661 612 575 490 382 216 78


Source: OPTN/SRTR Data as of May 4, 2009.

(-) = None in category.

(1) Genito-Urinary: kidney, bladder, uterine cervix, uterine body, ovarian, vulva, testicular, prostate.

(2) Gastro-Intestinal: tongue, throat, esophagus, stomach, small intestine, colo-rectal, liver and biliary tract, pancreas.

(3) Sarcoma: fibrosarcoma, osteosarcoma, etc.

Recipient malignancy statistics are based on voluntary reporting to the OPTN.



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