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Table 13.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1998 to 2007

Recipients with Heart-Lung Transplants

  Year of Transplant
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Transplants 47 51 48 27 33 29 40 35 31 31
Tx with Follow-up Immunosuppression Info 24 28 29 21 21 13 30 26 20 26
Corticosteroids Any in Category 95.8% 96.4% 100.0% 95.2% 100.0% 92.3% 100.0% 100.0% 100.0% 100.0%
Steroids 95.8% 96.4% 100.0% 95.2% 100.0% 92.3% 100.0% 100.0% 100.0% 100.0%
Cyclosporine Any in Category 62.5% 53.6% 58.6% 47.6% 52.4% 38.5% 36.7% 50.0% 15.0% 7.7%
Sandimmmune 0.0% 0.0% 6.9% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Neoral 62.5% 53.6% 44.8% 42.9% 47.6% 23.1% 26.7% 30.8% 5.0% 3.8%
Gengraf 0.0% 0.0% 6.9% 4.8% 4.8% 15.4% 10.0% 19.2% 10.0% 3.8%
Eon 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tacrolimus Any in Category 37.5% 50.0% 58.6% 76.2% 66.7% 76.9% 73.3% 84.6% 90.0% 96.2%
Tacrolimus 37.5% 50.0% 58.6% 76.2% 66.7% 76.9% 73.3% 84.6% 90.0% 96.2%
Antimetabolites Any in Category 95.8% 89.3% 93.1% 95.2% 95.2% 84.6% 90.0% 100.0% 100.0% 76.9%
Mycophenolate Mofetil 54.2% 42.9% 48.3% 47.6% 38.1% 38.5% 43.3% 53.8% 60.0% 65.4%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 3.8%
Azathioprine 41.7% 46.4% 44.8% 47.6% 57.1% 46.2% 46.7% 46.2% 40.0% 7.7%
Cytoxan 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 4.2% 3.6% 10.3% 0.0% 9.5% 0.0% 6.7% 7.7% 0.0% 3.8%
Sirolimus 4.2% 3.6% 10.3% 0.0% 9.5% 0.0% 6.7% 7.7% 0.0% 3.8%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 4, 2009.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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