Your browser does not support JavaScript capabilities, which maybe required to display this page properly.


PDF FormatRequires Adobe Acrobat Reader

Table 13.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1998 to 2007

Recipients with Heart-Lung Transplants

  Transplant Year
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Transplants 47 51 48 27 33 29 40 35 31 31
Functioning Graft at 1 Year PostTx 24 28 29 21 21 13 31 26 20 27
With Maintenance Use Recorded at 1 Year PostTx 13 26 28 21 21 13 30 26 20 26
Tac 0.0% 0.0% 3.6% 0.0% 0.0% 7.7% 0.0% 3.8% 0.0% 0.0%
CyA + MMF/MPA 7.7% 0.0% 0.0% 4.8% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA 0.0% 0.0% 0.0% 9.5% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 3.8% 0.0% 0.0%
CyA + Steroids 0.0% 7.7% 7.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + Steroids 23.1% 0.0% 7.1% 14.3% 9.5% 7.7% 10.0% 7.7% 15.0% 42.3%
--- + MMF/MPA + Steroids 0.0% 0.0% 3.6% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + MMF/MPA + Steroids 38.5% 19.2% 3.6% 14.3% 14.3% 7.7% 13.3% 7.7% 0.0% 7.7%
Tac + MMF/MPA + Steroids 7.7% 23.1% 32.1% 23.8% 28.6% 38.5% 36.7% 50.0% 60.0% 38.5%
--- + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.0% 4.8% 0.0% 3.3% 0.0% 5.0% 0.0%
CyA + OtherAntimet + Steroids 15.4% 23.1% 17.9% 4.8% 14.3% 15.4% 10.0% 7.7% 5.0% 0.0%
Tac + OtherAntimet + Steroids 7.7% 23.1% 14.3% 28.6% 19.0% 23.1% 20.0% 15.4% 10.0% 7.7%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 4.8% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + Siro/Evero + Steroids 0.0% 0.0% 3.6% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + Siro/Evero + Steroids 0.0% 3.8% 3.6% 0.0% 0.0% 0.0% 6.7% 3.8% 0.0% 0.0%
Other Regimen 0.0% 0.0% 3.6% 0.0% 4.8% 0.0% 0.0% 0.0% 5.0% 3.8%


Source: OPTN/SRTR Data as of May 4, 2009.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.



PDF FormatRequires Adobe Acrobat Reader