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Table 13.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1998 to 2007

Recipients with Heart-Lung Transplants

  Year of Transplant
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Functioning Graft at Discharge 31 34 33 21 22 17 35 29 24 27
With Immunosuppression Info 29 33 33 21 22 17 35 29 24 26
Corticosteroids Any in Category 89.7% 100.0% 100.0% 100.0% 100.0% 94.1% 100.0% 100.0% 100.0% 100.0%
Steroids 89.7% 100.0% 100.0% 100.0% 100.0% 94.1% 100.0% 100.0% 100.0% 100.0%
Cyclosporine Any in Category 72.4% 66.7% 81.8% 71.4% 59.1% 47.1% 37.1% 48.3% 29.2% 3.8%
Sandimmmune 10.3% 18.2% 6.1% 9.5% 13.6% 5.9% 0.0% 0.0% 0.0% 0.0%
Neoral 62.1% 48.5% 72.7% 57.1% 40.9% 23.5% 22.9% 31.0% 12.5% 3.8%
Gengraf 0.0% 0.0% 3.0% 4.8% 4.5% 17.6% 14.3% 13.8% 16.7% 0.0%
Eon 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 3.4% 0.0% 0.0%
Tacrolimus Any in Category 27.6% 39.4% 27.3% 23.8% 45.5% 52.9% 65.7% 55.2% 75.0% 96.2%
Tacrolimus 27.6% 39.4% 27.3% 23.8% 45.5% 52.9% 65.7% 55.2% 75.0% 96.2%
Antimetabolites Any in Category 82.8% 84.8% 93.9% 95.2% 95.5% 82.4% 82.9% 96.6% 91.7% 84.6%
Mycophenolate Mofetil 34.5% 48.5% 45.5% 52.4% 40.9% 29.4% 54.3% 55.2% 70.8% 65.4%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 3.8%
Azathioprine 48.3% 36.4% 48.5% 42.9% 54.5% 52.9% 28.6% 41.4% 20.8% 15.4%
mTOR Inhibitors Any in Category 0.0% 0.0% 0.0% 0.0% 0.0% 5.9% 2.9% 0.0% 0.0% 0.0%
Sirolimus 0.0% 0.0% 0.0% 0.0% 0.0% 5.9% 2.9% 0.0% 0.0% 0.0%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2008.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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