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Table 12.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1997 to 2006

Recipients with Lung Transplants

  Year of Transplant
1997 1998 1999 2000 2001 2002 2003 2004 2005 2006
Transplants 948 893 922 977 1,083 1,054 1,099 1,185 1,407 1,406
Tx with Follow-up Immunosuppression Info 671 627 665 735 804 828 883 982 1,121 1,145
Corticosteroids Any in Category 98.2% 99.5% 99.1% 98.6% 99.5% 97.0% 97.8% 99.3% 99.2% 97.8%
Steroids 98.2% 99.5% 99.1% 98.6% 99.5% 97.0% 97.8% 99.3% 99.2% 97.8%
Cyclosporine Any in Category 62.0% 64.0% 63.8% 54.6% 45.9% 35.3% 30.8% 24.5% 23.0% 17.0%
Cyclosporin 0.0% 0.0% 0.0% 0.3% 0.5% 0.1% 0.0% 0.1% 0.5% 1.4%
Sandimmmune 8.0% 6.5% 4.7% 4.2% 5.0% 2.5% 2.7% 1.3% 1.8% 1.7%
Neoral 53.8% 57.4% 58.6% 48.2% 34.0% 26.0% 20.7% 17.5% 14.9% 9.3%
Gengraf 0.1% 0.0% 0.3% 1.9% 6.3% 6.5% 7.1% 5.6% 5.5% 4.6%
Eon 0.0% 0.0% 0.2% 0.0% 0.1% 0.1% 0.2% 0.0% 0.3% 0.1%
Tacrolimus Any in Category 37.7% 41.9% 46.6% 55.6% 69.2% 75.7% 76.2% 83.6% 85.7% 88.6%
Tacrolimus 37.7% 41.9% 46.6% 55.6% 69.2% 75.7% 76.2% 83.6% 85.7% 88.6%
Antimetabolites Any in Category 88.5% 93.0% 91.4% 94.3% 90.8% 88.8% 87.7% 88.7% 91.8% 92.4%
Mycophenolate Mofetil 30.4% 30.3% 33.8% 40.8% 42.3% 45.0% 46.5% 49.3% 52.1% 52.0%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 3.4% 3.0%
Azathioprine 57.5% 62.5% 57.6% 53.3% 48.1% 43.7% 41.1% 39.2% 36.1% 37.5%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.2% 0.0% 0.0% 0.0% 0.2% 0.0%
Cytoxan 0.6% 0.2% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 0.3% 6.2% 6.3% 11.1% 14.4% 10.3% 8.6% 7.9% 6.7%
Sirolimus 0.0% 0.2% 5.9% 6.3% 11.1% 14.4% 10.3% 8.6% 7.9% 6.7%
Everolimus 0.0% 0.2% 0.3% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2008.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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