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Table 12.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1998 to 2007

Recipients with Lung Transplants

  Year of Transplant
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Functioning Graft at Discharge 753 801 859 951 947 1,013 1,108 1,289 1,302 1,361
With Immunosuppression Info 751 789 854 948 942 1,009 1,098 1,271 1,296 1,325
Corticosteroids Any in Category 97.3% 98.1% 97.8% 98.9% 98.6% 94.4% 97.2% 98.0% 97.5% 95.3%
Steroids 97.3% 98.1% 97.8% 98.9% 98.6% 94.4% 97.2% 98.0% 97.5% 95.3%
Cyclosporine Any in Category 73.4% 66.7% 61.9% 52.1% 42.5% 34.6% 29.7% 22.3% 16.2% 10.1%
Cyclosporin 0.0% 0.0% 0.0% 0.4% 0.2% 0.2% 0.2% 0.5% 1.1% 1.1%
Sandimmmune 11.9% 10.8% 6.9% 5.7% 4.5% 4.8% 2.1% 1.7% 1.6% 0.8%
Neoral 61.5% 55.8% 54.0% 39.3% 31.0% 23.0% 20.4% 15.1% 9.3% 6.9%
Gengraf 0.0% 0.0% 1.1% 6.2% 6.7% 6.5% 6.7% 4.8% 4.2% 1.4%
Eon 0.0% 0.1% 0.0% 0.4% 0.1% 0.1% 0.3% 0.2% 0.0% 0.0%
Tacrolimus Any in Category 26.6% 29.9% 38.3% 49.4% 57.2% 65.4% 69.9% 76.1% 82.6% 87.5%
Tacrolimus 26.6% 29.9% 38.3% 49.4% 57.2% 65.4% 69.9% 76.1% 82.6% 87.5%
Antimetabolites Any in Category 92.1% 91.8% 93.7% 91.8% 91.1% 89.6% 90.6% 92.1% 92.7% 92.2%
Mycophenolate Mofetil 22.1% 27.5% 35.6% 41.4% 45.1% 43.5% 46.7% 51.5% 51.9% 54.3%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 2.1% 2.5% 6.4%
Azathioprine 69.9% 64.0% 57.8% 50.2% 45.8% 46.1% 43.9% 38.3% 38.3% 31.5%
Leflunomide 0.0% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0%
Cytoxan 0.1% 0.3% 0.1% 0.1% 0.2% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.1% 0.6% 2.6% 4.2% 1.9% 1.1% 1.3% 0.6% 1.7% 0.2%
Sirolimus 0.1% 0.6% 2.6% 4.2% 1.9% 1.1% 1.3% 0.6% 1.7% 0.2%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2008.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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