Table 12.6d

Immunosuppression Use for Maintenance by Regimen

Prior to Discharge, 1998 to 2007

Recipients with Lung Transplants

	Transplant Year
	1998	1999	2000	2001	2002	2003	2004	2005	2006	2007
Functioning Graft at Discharge	753	801	859	951	947	1,013	1,108	1,289	1,302	1,361
With Immunosuppression Info	751	789	854	948	942	1,009	1,098	1,271	1,296	1,325
CyA	0.3%	0.3%	0.1%	0.0%	0.0%	0.0%	0.1%	0.0%	0.1%	0.0%
Tac	0.1%	0.0%	0.1%	0.0%	0.1%	1.0%	0.1%	0.4%	0.1%	0.5%
--- + MMF/MPA	0.0%	0.1%	0.0%	0.1%	0.1%	0.0%	0.0%	0.0%	0.0%	0.1%
CyA + MMF/MPA	0.1%	0.0%	0.5%	0.1%	0.1%	0.2%	0.1%	0.2%	0.1%	0.0%
Tac + MMF/MPA	0.0%	0.0%	0.9%	0.1%	0.1%	0.8%	0.5%	0.6%	1.5%	1.6%
--- + OtherAntimet	0.0%	0.1%	0.0%	0.0%	0.1%	0.0%	0.0%	0.0%	0.0%	0.1%
CyA + OtherAntimet	1.6%	1.1%	0.1%	0.1%	0.3%	0.7%	0.4%	0.1%	0.1%	0.0%
Tac + OtherAntimet	0.4%	0.0%	0.2%	0.2%	0.2%	2.3%	1.5%	0.6%	0.3%	2.0%
--- + MMF/MPA + OtherAntimet	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.1%	0.0%
Tac + MMF/MPA + OtherAntimet	0.0%	0.0%	0.0%	0.1%	0.0%	0.1%	0.0%	0.1%	0.1%	0.1%
Tac + MMF/MPA + Siro/Evero	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.0%	0.1%	0.1%	0.0%
--- + Steroids	0.8%	1.0%	0.9%	0.7%	0.7%	1.2%	0.5%	1.0%	0.5%	0.9%
CyA + Steroids	4.4%	4.3%	2.9%	2.4%	1.4%	1.2%	1.1%	1.1%	1.5%	0.6%
Tac + Steroids	2.0%	2.0%	1.4%	1.7%	5.7%	6.0%	7.0%	4.8%	4.0%	5.1%
--- + MMF/MPA + Steroids	0.3%	0.4%	0.4%	0.4%	0.2%	0.3%	0.2%	0.8%	0.3%	0.7%
CyA + MMF/MPA + Steroids	13.4%	15.0%	15.5%	17.8%	17.5%	13.6%	10.0%	7.9%	6.4%	2.0%
Tac + MMF/MPA + Steroids	8.1%	12.0%	16.3%	18.8%	25.4%	27.1%	35.2%	43.7%	45.7%	55.9%
--- + OtherAntimet + Steroids	0.8%	2.0%	0.0%	0.5%	0.0%	0.2%	0.4%	0.2%	0.3%	0.9%
CyA + OtherAntimet + Steroids	50.5%	44.1%	39.9%	27.1%	20.7%	16.0%	15.9%	12.3%	7.3%	6.8%
Tac + OtherAntimet + Steroids	13.6%	14.8%	16.0%	20.9%	23.0%	24.9%	23.4%	24.5%	28.4%	21.5%
--- + Siro/Evero + Steroids	0.0%	0.0%	0.0%	0.1%	0.1%	0.2%	0.0%	0.0%	0.0%	0.0%
CyA + Siro/Evero + Steroids	0.0%	0.0%	0.0%	0.1%	0.3%	0.1%	0.0%	0.0%	0.0%	0.0%
Tac + Siro/Evero + Steroids	0.0%	0.4%	0.6%	2.5%	0.1%	0.0%	0.4%	0.2%	0.8%	0.1%
Other Regimen	3.6%	2.3%	4.1%	6.1%	3.7%	4.3%	3.3%	1.5%	2.5%	1.3%

Source: OPTN/SRTR Data as of May 1, 2008.

Percentages in each column sum to 100 percent.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.