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Table 11.6i

Immunosuppression Use for Antirejection Treatment from Transplant

to One Year Following Transplantation, 1998 to 2007

Recipients with Heart Transplants

  Year of Transplant
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Transplants 2,348 2,188 2,199 2,202 2,155 2,057 2,015 2,125 2,193 2,209
Tx with Antirejection Treatments 980 916 901 849 803 656 533 533 488 430
Antibodies Any in Category 21.3% 17.7% 16.3% 15.5% 17.4% 18.4% 15.6% 18.0% 19.3% 17.0%
Atgam/NRATG/NRATS 7.2% 6.3% 4.6% 3.9% 4.0% 4.6% 2.6% 2.4% 3.7% 5.1%
OKT3 15.0% 7.4% 5.1% 5.8% 6.8% 4.1% 3.2% 3.4% 3.7% 1.4%
Thymoglobulin 0.2% 2.0% 3.8% 4.9% 6.4% 7.5% 8.6% 9.4% 11.3% 9.3%
Zenapax 0.8% 2.5% 3.0% 2.5% 1.5% 2.0% 1.5% 3.6% 1.6% 2.6%
Simulect 0.1% 0.9% 2.0% 0.4% 0.4% 1.4% 0.6% 0.8% 0.4% 0.2%
Campath 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.2% 0.2% 0.0%
Corticosteroids Any in Category 87.8% 91.3% 92.3% 92.7% 92.2% 92.5% 91.4% 90.8% 90.4% 89.5%
Steroids 87.8% 91.3% 92.3% 92.7% 92.2% 92.5% 91.4% 90.8% 90.4% 89.5%
Antimetabolites Any in Category 6.5% 4.6% 4.4% 2.0% 3.0% 3.5% 1.7% 2.3% 1.8% 2.3%
Cytoxan 2.4% 2.1% 1.7% 0.5% 0.9% 1.7% 1.3% 1.3% 1.6% 2.1%
Methotrexate 4.3% 2.6% 2.8% 1.5% 2.1% 1.8% 0.4% 0.9% 0.2% 0.2%


Source: OPTN/SRTR Data as of May 4, 2009.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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