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Table 11.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1999 to 2008

Recipients with Heart Transplants

  Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Functioning Graft at Discharge 1,922 1,982 2,008 1,977 1,899 1,867 1,958 2,040 2,070 2,039
With Immunosuppression Info 1,912 1,976 1,983 1,966 1,885 1,853 1,936 1,999 2,059 2,026
Corticosteroids Any in Category 95.5% 94.4% 97.2% 96.9% 92.6% 92.0% 93.3% 92.2% 88.8% 87.4%
Steroids 95.5% 94.4% 97.2% 96.9% 92.6% 92.0% 93.3% 92.2% 88.8% 87.4%
Cyclosporine Any in Category 82.7% 80.4% 70.3% 60.1% 58.5% 50.9% 40.1% 38.1% 33.0% 25.6%
Cyclosporin 0.1% 0.1% 0.1% 0.1% 0.1% 0.2% 0.6% 1.4% 1.1% 1.5%
Sandimmmune 11.2% 8.1% 4.3% 2.8% 3.4% 2.9% 2.1% 1.5% 1.2% 0.6%
Neoral 71.4% 70.6% 57.7% 44.5% 40.6% 33.3% 25.5% 26.8% 23.5% 17.6%
Gengraf 0.0% 1.6% 8.1% 12.6% 14.3% 14.2% 11.2% 8.3% 7.0% 5.5%
Eon 0.0% 0.0% 0.2% 0.2% 0.1% 0.4% 0.7% 0.2% 0.2% 0.3%
Tacrolimus Any in Category 14.1% 16.0% 30.2% 39.6% 41.7% 47.0% 57.8% 59.6% 65.4% 73.1%
Tacrolimus 14.1% 16.0% 30.2% 39.6% 41.7% 47.0% 57.8% 59.6% 65.0% 72.5%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.6%
Antimetabolites Any in Category 82.6% 88.2% 91.0% 84.4% 89.2% 94.9% 94.3% 91.4% 91.9% 92.5%
Mycophenolate Mofetil 50.8% 68.3% 75.8% 71.7% 79.6% 85.3% 84.8% 83.4% 85.6% 87.1%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.4% 0.2% 0.1% 1.4% 3.4% 3.4% 2.7%
Azathioprine 31.5% 19.5% 14.9% 12.2% 9.3% 9.6% 8.1% 4.7% 2.9% 2.8%
Leflunomide 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Cytoxan 0.3% 0.4% 0.3% 0.2% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 1.4% 2.9% 4.3% 10.0% 8.4% 5.3% 4.2% 6.2% 4.5% 3.4%
Sirolimus 0.9% 2.6% 4.3% 10.0% 8.4% 5.2% 3.8% 3.7% 1.2% 1.0%
Everolimus 0.5% 0.4% 0.0% 0.1% 0.0% 0.2% 0.4% 2.6% 3.3% 2.4%


Source: OPTN/SRTR Data as of May 4, 2009.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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