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Table 11.6b

Immunosuppression Use for Induction by Discharge Regimen, 2004 to 2008

Recipients with Heart Transplants

  Discharge Regimen (w/ or w/o Steroids Use) All
CyA Tac CyA+ MMF Tac+ MMF CyA+ Aza Tac+ Aza Siro+ MMF CyA+ Siro Tac+ Siro Other
Functioning Graft with Immunosuppression Info at Discharge 91 266 2,955 5,306 221 118 78 8 76 754 9,873
% of All Regimens 0.9% 2.7% 29.9% 53.7% 2.2% 1.2% 0.8% 0.1% 0.8% 7.6% 100.0%
Induction Drug 8.8% 7.1% 5.3% 4.9% 9.5% 6.8% 7.7% 37.5% 5.3% 16.6% 6.2%
Atgam/NRATG/NRATS
OKT3 2.2% 0.0% 2.6% 1.8% 28.1% 5.9% 1.3% 0.0% 3.9% 6.9% 3.0%
Thymoglobulin 9.9% 11.3% 14.0% 18.8% 20.4% 38.1% 21.8% 12.5% 55.3% 25.2% 18.1%
Zenapax 4.4% 1.1% 21.1% 10.6% 3.2% 2.5% 9.0% 12.5% 0.0% 31.0% 14.7%
Simulect 13.2% 8.6% 13.1% 14.9% 5.0% 3.4% 12.8% 25.0% 1.3% 21.6% 14.2%
Campath 1.1% 7.9% 0.1% 3.0% 0.5% 0.0% 6.4% 0.0% 0.0% 2.9% 2.2%
No Induction Drugs Recorded 64.8% 65.0% 45.7% 49.7% 34.4% 43.2% 43.6% 37.5% 35.5% 47.2% 48.3%


Source: OPTN/SRTR Data as of May 4, 2009.

Individual induction drug percentages will not necessarily add up to 100 percent, as patients may be prescribed more than one induction drug.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.



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