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Table 1.9c

Immunosuppression Use by Organ

Maintenance Regimen at One Year Following Transplantation

2006 Transplants

  Organ
Heart-Lung Heart Intestine Kidney KP Liver Lung PAK PTA
Transplants 31 2,193 175 17,091 924 6,650 1,406 293 173
With Maintenance Use Recorded at 1 Year PostTx 20 1,879 120 15,092 803 5,245 1,141 218 122
Maintenance Regimen CyA 0.0% 0.3% 0.8% 0.2% 0.1% 1.9% 0.2% 0.0% 0.0%
Tac 0.0% 2.8% 33.3% 2.6% 2.0% 26.6% 0.2% 1.8% 16.4%
--- + MMF/MPA 0.0% 0.4% 0.0% 0.3% 0.4% 0.4% 0.2% 0.0% 0.8%
CyA + MMF/MPA 0.0% 6.8% 0.0% 1.8% 0.4% 3.0% 0.2% 1.4% 0.8%
Tac + MMF/MPA 0.0% 16.3% 0.0% 24.1% 18.9% 22.0% 1.2% 19.3% 13.1%
--- + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet 0.0% 1.1% 0.0% 0.0% 0.1% 0.0% 0.1% 0.0% 0.0%
Tac + OtherAntimet 0.0% 1.2% 0.0% 0.4% 0.1% 0.2% 0.2% 0.0% 0.0%
--- + MMF/MPA + OtherAntimet 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0%
--- + Siro/Evero 0.0% 0.0% 0.8% 0.2% 0.0% 1.9% 0.0% 0.0% 0.0%
CyA + Siro/Evero 0.0% 0.4% 0.0% 0.8% 2.4% 0.3% 0.1% 2.3% 0.8%
Tac + Siro/Evero 0.0% 1.2% 3.3% 1.2% 3.4% 1.2% 0.1% 4.6% 6.6%
--- + MMF/MPA + Siro/Evero 0.0% 0.5% 0.0% 2.0% 1.0% 2.2% 0.0% 1.4% 0.0%
CyA + MMF/MPA + Siro/Evero 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + MMF/MPA + Siro/Evero 0.0% 0.5% 0.8% 0.5% 3.2% 0.2% 0.1% 1.8% 11.5%
--- + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet + Siro/Evero 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + OtherAntimet + Siro/Evero 0.0% 0.1% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.8%
--- + Steroids 0.0% 0.2% 0.0% 0.3% 0.4% 0.2% 0.5% 0.0% 0.0%
CyA + Steroids 0.0% 1.2% 0.8% 0.4% 0.2% 1.2% 1.5% 0.0% 0.0%
Tac + Steroids 15.0% 2.7% 46.7% 4.2% 3.7% 15.0% 8.5% 3.7% 24.6%
--- + MMF/MPA + Steroids 0.0% 0.4% 0.0% 1.3% 0.4% 0.5% 0.5% 1.8% 0.0%
CyA + MMF/MPA + Steroids 0.0% 18.6% 0.0% 6.5% 2.0% 1.5% 4.1% 2.8% 0.0%
Tac + MMF/MPA + Steroids 60.0% 35.4% 5.0% 44.0% 53.5% 17.4% 47.5% 50.9% 21.3%
--- + OtherAntimet + Steroids 5.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.5% 0.5% 0.0%
CyA + OtherAntimet + Steroids 5.0% 1.1% 0.0% 0.2% 0.0% 0.0% 4.6% 0.0% 0.0%
Tac + OtherAntimet + Steroids 10.0% 1.5% 0.8% 1.1% 1.2% 0.2% 22.0% 1.8% 0.0%
--- + Siro/Evero + Steroids 0.0% 0.3% 0.0% 0.4% 0.1% 1.1% 0.1% 0.5% 0.0%
CyA + Siro/Evero + Steroids 0.0% 2.1% 0.0% 1.0% 0.6% 0.0% 0.4% 0.5% 0.8%
Tac + Siro/Evero + Steroids 0.0% 1.5% 7.5% 1.7% 3.1% 0.9% 3.4% 3.7% 0.8%
Other Regimen 5.0% 3.5% 0.0% 4.6% 2.4% 1.8% 3.8% 1.4% 1.6%


Source: OPTN/SRTR Data as of May 1, 2008.

Percentages are calculated based on the total number of patients with functioning graft and having any immunosuppression information reported at 1yr post-transplant.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF/MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.



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