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Table 1.9a

Immunosuppression Use by Organ in 2006 and 2007

  Organ
Heart-Lung Heart Intestine Kidney KP Liver Lung PAK PTA
Transplants (2007)   29 2,207 198 16,623 862 6,489 1,471 261 208
Tx With Immunosuppression Info at Discharge   27 2,135 194 16,114 840 6,207 1,404 247 197
Induction Drug Reported 81.5% 53.9% 49.0% 78.0% 78.0% 25.8% 62.3% 80.2% 67.0%
Induction Drugs Atgam/NRATG/NRATS 33.3% 4.2% 0.5% 1.1% 1.8% 1.2% 5.8% 1.2% 1.0%
OKT3 7.4% 3.2% 17.5% 1.2% 1.2% 2.9% 1.0% 0.4% 7.6%
Thymoglobulin 0.0% 19.2% 23.7% 43.8% 52.0% 9.6% 4.3% 61.9% 42.1%
Zenapax 11.1% 12.7% 9.8% 10.8% 6.5% 8.2% 16.2% 2.0% 7.1%
Simulect 25.9% 14.2% 2.1% 16.6% 5.7% 5.6% 25.9% 4.0% 3.6%
Campath 18.5% 2.6% 13.4% 9.5% 13.2% 1.4% 9.8% 12.1% 13.7%
Tx With Immunosuppression Info and Functioning Graft at Discharge   26 2,044 166 15,884 826 5,902 1,325 228 182
Maintenance at Discharge Corticosteroids Use   100.0% 88.7% 77.1% 65.9% 65.4% 75.9% 95.3% 58.3% 58.2%
Steroids 100.0% 88.7% 77.1% 65.9% 65.4% 75.9% 95.3% 58.3% 58.2%
Calcineurin Inhibitor Use   100.0% 97.9% 97.0% 95.6% 98.3% 97.9% 97.6% 97.8% 97.3%
Cyclosporine 3.8% 33.0% 0.0% 10.1% 4.5% 7.2% 10.1% 4.8% 2.2%
Tacrolimus 96.2% 64.9% 97.0% 85.4% 93.8% 90.7% 87.5% 93.0% 95.1%
Antimetabolite Use   84.6% 91.9% 22.9% 92.1% 91.2% 72.8% 92.2% 94.3% 59.3%
Mycophenolate Mofetil 65.4% 85.6% 21.1% 75.0% 73.2% 67.2% 54.3% 83.8% 52.2%
Mycophenolate Sodium 3.8% 3.4% 0.0% 16.4% 17.2% 4.9% 6.4% 9.2% 5.5%
Azathioprine 15.4% 2.8% 1.8% 0.6% 0.7% 0.6% 31.5% 1.3% 1.6%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
mTOR Inhibitor Use   0.0% 4.5% 9.0% 5.2% 10.5% 2.5% 0.2% 7.9% 17.0%
Sirolimus 0.0% 1.2% 9.0% 4.8% 10.5% 2.5% 0.2% 7.9% 17.0%
Everolimus 0.0% 3.3% 0.0% 0.4% 0.0% 0.0% 0.0% 0.0% 0.0%
Transplants (2006)   31 2,193 175 17,091 924 6,650 1,406 293 173
Tx With Maintenance Use at 1yr PostTx   20 1,879 120 15,092 803 5,245 1,141 218 122
Maintenance at 1yr PostTx Corticosteroids Use   100.0% 68.4% 60.8% 65.8% 67.6% 39.6% 97.4% 67.4% 48.4%
Steroids 100.0% 68.4% 60.8% 65.8% 67.6% 39.6% 97.4% 67.4% 48.4%
Calcineurin Inhibitor Use   95.0% 96.5% 99.2% 91.7% 96.4% 92.7% 96.8% 95.0% 99.2%
Cyclosporine 5.0% 32.0% 1.7% 11.2% 6.2% 8.3% 11.2% 6.9% 2.5%
Tacrolimus 90.0% 64.5% 97.5% 80.6% 90.2% 84.5% 85.5% 88.1% 96.7%
Antimetabolite Use   85.0% 87.1% 6.7% 86.7% 83.8% 49.3% 84.6% 83.0% 50.0%
Mycophenolate Mofetil 60.0% 76.7% 5.8% 67.7% 57.7% 44.1% 51.3% 67.4% 35.2%
Mycophenolate Sodium 0.0% 5.1% 0.0% 16.9% 24.4% 4.7% 4.6% 13.3% 13.9%
Azathioprine 25.0% 5.2% 0.8% 1.4% 1.0% 0.6% 28.7% 1.4% 0.8%
Leflunomide 0.0% 0.2% 0.0% 0.8% 0.7% 0.0% 0.0% 0.9% 0.0%
mTOR Inhibitor Use   0.0% 9.3% 12.5% 11.3% 16.1% 9.4% 6.1% 16.1% 22.1%
Sirolimus 0.0% 7.6% 12.5% 10.8% 16.1% 9.4% 6.1% 16.1% 22.1%
Everolimus 0.0% 1.6% 0.0% 0.5% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2008.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.

Induction drugs include any reported antilymphocyte antibodies and antibodies directed against lymphocyte receptors.



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