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Table 10.6g

Immunosuppression Use for Maintenance Between Discharge

and One Year Following Transplantation, 1998 to 2007

Recipients with Intestine Transplants

  Year of Transplant
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007
Transplants 70 73 82 113 107 116 152 178 175 198
Tx with Follow-up Immunosuppression Info 34 37 55 69 73 88 113 130 120 139
Corticosteroids Any in Category 97.1% 100.0% 100.0% 85.5% 90.4% 83.0% 78.8% 79.2% 86.7% 85.6%
Steroids 97.1% 100.0% 100.0% 85.5% 90.4% 83.0% 78.8% 79.2% 86.7% 85.6%
Cyclosporine Any in Category 2.9% 2.7% 0.0% 0.0% 1.4% 0.0% 0.9% 1.5% 1.7% 1.4%
Sandimmmune 0.0% 2.7% 0.0% 0.0% 1.4% 0.0% 0.0% 0.0% 0.0% 0.7%
Neoral 2.9% 0.0% 0.0% 0.0% 0.0% 0.0% 0.9% 0.8% 1.7% 0.7%
Gengraf 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8% 0.0% 0.0%
Tacrolimus Any in Category 100.0% 100.0% 100.0% 100.0% 100.0% 98.9% 97.3% 98.5% 98.3% 97.1%
Tacrolimus 100.0% 100.0% 100.0% 100.0% 100.0% 98.9% 97.3% 98.5% 98.3% 97.1%
Antimetabolites Any in Category 41.2% 37.8% 14.5% 15.9% 11.0% 10.2% 12.4% 20.0% 16.7% 18.7%
Mycophenolate Mofetil 35.3% 21.6% 14.5% 2.9% 9.6% 10.2% 8.0% 13.8% 13.3% 12.9%
Azathioprine 5.9% 16.2% 0.0% 13.0% 1.4% 0.0% 4.4% 6.2% 3.3% 5.8%
mTOR Inhibitors Any in Category 0.0% 21.6% 69.1% 24.6% 28.8% 15.9% 22.1% 23.8% 19.2% 10.8%
Sirolimus 0.0% 21.6% 69.1% 24.6% 28.8% 15.9% 22.1% 23.8% 19.2% 10.8%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 4, 2009.

Percentages are calculated based on the total number of patients with any immunosuppression use between discharge and one year following transplantation.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may be prescribed more than one drug within the same category.



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