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Table 6.6h

Persistency of Discharge Regimen by Follow-up Period, 2003 to 2007

Recipients with Pancreas Transplant Alone (PTA) Transplants

  Year of Transplant
2003 2004 2005 2006 2007
Discharge Regimen (w/ or w/o Steroid Use) CyA+MMF At Discharge (N) 2 1 - 2 3
At Discharge (%) 100.0% 100.0% - 100.0% 100.0%
6 Months PostTx (%) 100.0% 100.0% - 0.0% 100.0%
1 Year PostTx (%) 100.0% 100.0% - 0.0% 66.7%
2 Years PostTx (%) 50.0% 100.0% - 0.0% -
3 Years PostTx (%) 0.0% 100.0% - 0.0% -
CyA+Siro At Discharge (N) 1 1 - 1 -
At Discharge (%) 100.0% 100.0% - 100.0% -
6 Months PostTx (%) 100.0% - - 100.0% -
1 Year PostTx (%) - - - 100.0% -
2 Years PostTx (%) - - - - -
3 Years PostTx (%) - - - - -
Siro+MMF At Discharge (N) 1 - 2 - -
At Discharge (%) 100.0% - 100.0% - -
6 Months PostTx (%) 100.0% - 100.0% - -
1 Year PostTx (%) 100.0% - 100.0% - -
2 Years PostTx (%) 100.0% - 0.0% - -
3 Years PostTx (%) 0.0% - 0.0% - -
Tac+Aza At Discharge (N) - 2 - - 2
At Discharge (%) - 100.0% - - 100.0%
6 Months PostTx (%) - 100.0% - - 100.0%
1 Year PostTx (%) - 100.0% - - 100.0%
2 Years PostTx (%) - 50.0% - - -
3 Years PostTx (%) - 50.0% - - -
Tac+MMF At Discharge (N) 61 62 91 61 79
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 86.9% 78.7% 89.9% 85.2% 88.5%
1 Year PostTx (%) 75.2% 70.5% 84.3% 73.8% 78.9%
2 Years PostTx (%) 55.1% 62.1% 72.9% 62.5% -
3 Years PostTx (%) 48.5% 49.9% 67.6% 62.5% -
Tac+Siro At Discharge (N) 18 13 18 16 8
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 66.7% 84.6% 77.8% 81.3% 50.0%
1 Year PostTx (%) 61.1% 61.5% 72.2% 37.5% 50.0%
2 Years PostTx (%) 50.0% 46.2% 55.6% 18.8% -
3 Years PostTx (%) 43.8% 46.2% 42.9% - -


Source: OPTN/SRTR Data as of May 4, 2009.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen (CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up period, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.



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