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Table 14.2

Recipient Recurrence of Pretransplant Malignancies, 1999 to 2008

by Transplant Type

Organ Type Year of Transplant
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008
Total Total Recipients 22,046 23,274 24,256 24,921 25,486 27,051 28,117 28,939 28,364 27,961
# With Pre-Tx Malignancy (1) 743 874 1,004 1,203 1,211 1,289 1,409 1,577 1,693 1,833
# With Recurrence of Pre-Tx Malignancy (2) 60 56 63 77 68 49 64 54 37 33
% With Recurrence of Pre-Tx Malignancy (3) 8.1% 6.4% 6.3% 6.4% 5.6% 3.8% 4.5% 3.4% 2.2% 1.8%
# With Recurrence, but no Pre-Tx Malignancy (4) 39 45 76 84 97 116 127 109 73 28
Heart-Lung Total Recipients 51 48 27 33 29 40 35 31 31 27
# With Pre-Tx Malignancy (1) - 1 2 1 3 1 1 - 1 4
# With Recurrence of Pre-Tx Malignancy (2) - - - - - - - - - -
% With Recurrence of Pre-Tx Malignancy (3) - - - - - - - - - -
# With Recurrence, but no Pre-Tx Malignancy (4) - - - - - - - - - -
Heart Total Recipients 2,188 2,199 2,202 2,155 2,057 2,015 2,125 2,193 2,209 2,163
# With Pre-Tx Malignancy (1) 75 70 98 72 78 95 103 107 103 132
# With Recurrence of Pre-Tx Malignancy (2) 4 2 3 - 3 1 2 4 3 3
% With Recurrence of Pre-Tx Malignancy (3) 5.3% 2.9% 3.1% - 3.8% 1.1% 1.9% 3.7% 2.9% 2.3%
# With Recurrence, but no Pre-Tx Malignancy (4) 3 3 3 4 3 2 2 - 2 -
Intestine Total Recipients 73 82 113 107 116 152 178 175 198 185
# With Pre-Tx Malignancy (1) 1 4 4 3 6 9 2 5 9 10
# With Recurrence of Pre-Tx Malignancy (2) - 1 1 - 1 - - - - 1
% With Recurrence of Pre-Tx Malignancy (3) - 25.0% 25.0% - 16.7% - - - - 10.0%
# With Recurrence, but no Pre-Tx Malignancy (4) - - - - 1 - - - 1 1
Kidney Total Recipients 12,761 13,617 14,271 14,779 15,137 16,004 16,483 17,093 16,630 16,517
# With Pre-Tx Malignancy (1) 329 348 424 459 462 507 659 741 758 826
# With Recurrence of Pre-Tx Malignancy (2) 14 13 11 11 13 13 12 10 5 5
% With Recurrence of Pre-Tx Malignancy (3) 4.3% 3.7% 2.6% 2.4% 2.8% 2.6% 1.8% 1.3% 0.7% 0.6%
# With Recurrence, but no Pre-Tx Malignancy (4) 12 17 16 16 19 12 10 12 6 -
Kidney-Pancreas Total Recipients 941 915 891 905 871 881 903 924 862 836
# With Pre-Tx Malignancy (1) 11 8 13 9 9 9 13 18 10 10
# With Recurrence of Pre-Tx Malignancy (2) - - - - - - - - - -
% With Recurrence of Pre-Tx Malignancy (3) - - - - - - - - - -
# With Recurrence, but no Pre-Tx Malignancy (4) - 1 1 1 1 - - - - -
Liver Total Recipients 4,751 4,997 5,196 5,332 5,673 6,171 6,444 6,651 6,494 6,318
# With Pre-Tx Malignancy (1) 299 402 414 611 610 616 556 603 711 734
# With Recurrence of Pre-Tx Malignancy (2) 40 36 46 65 51 34 49 40 29 22
% With Recurrence of Pre-Tx Malignancy (3) 13.4% 9.0% 11.1% 10.6% 8.4% 5.5% 8.8% 6.6% 4.1% 3.0%
# With Recurrence, but no Pre-Tx Malignancy (4) 22 22 52 62 72 101 112 95 62 26
Lung Total Recipients 922 977 1,083 1,054 1,099 1,185 1,407 1,406 1,471 1,478
# With Pre-Tx Malignancy (1) 22 28 34 35 34 37 60 90 83 106
# With Recurrence of Pre-Tx Malignancy (2) 2 3 1 1 - 1 1 - - 1
% With Recurrence of Pre-Tx Malignancy (3) 9.1% 10.7% 2.9% 2.9% - 2.7% 1.7% - - 0.9%
# With Recurrence, but no Pre-Tx Malignancy (4) 2 2 4 1 - 1 2 2 - -
Pancreas After Kidney Total Recipients 220 305 305 375 344 420 343 293 261 214
# With Pre-Tx Malignancy (1) 3 8 8 8 5 10 8 9 10 3
# With Recurrence of Pre-Tx Malignancy (2) - - - - - - - - - -
% With Recurrence of Pre-Tx Malignancy (3) - - - - - - - - - -
# With Recurrence, but no Pre-Tx Malignancy (4) - - - - - - - - - -
Pancreas Transplant Alone Total Recipients 139 134 168 181 160 183 199 173 208 223
# With Pre-Tx Malignancy (1) 3 5 7 5 4 5 7 4 8 8
# With Recurrence of Pre-Tx Malignancy (2) - 1 1 - - - - - - 1
% With Recurrence of Pre-Tx Malignancy (3) - 20.0% 14.3% - - - - - - 12.5%
# With Recurrence, but no Pre-Tx Malignancy (4) - - - - 1 - 1 - 2 1


Source: OPTN/SRTR Data as of May 4, 2009.

(-) = None in category.

Includes both deceased and living donor transplants.

(1) Pre-Tx malignancy reported on the TCR or TRR Form.

(2) Recurrence reported on the Transplant Recipient Follow-up Form.

(3) Percent recurrence is calculated based on total with reported pre-tx malignancy.

(4) Recurrence reported on the follow-up form, but no pre-tx malignancy reported, so these are not included in recurrence rates.

Recipient malignancy statistics are based on voluntary reporting to the OPTN



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