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Table 1.9c

Immunosuppression Use by Organ

Maintenance Regimen at One Year Following Transplantation

2007 Transplants

  Organ
Heart-Lung Heart Intestine Kidney KP Liver Lung PAK PTA
Transplants 31 2,209 198 16,630 862 6,494 1,471 261 208
With Maintenance Use Recorded at 1 Year PostTx 26 1,896 139 14,693 755 5,131 1,150 206 150
Maintenance Regimen CyA 0.0% 0.4% 0.7% 0.1% 0.0% 2.1% 0.1% 0.0% 0.0%
Tac 0.0% 2.6% 27.3% 2.2% 1.3% 28.5% 0.3% 1.5% 7.3%
--- + MMF/MPA 0.0% 0.2% 0.0% 0.2% 0.0% 0.5% 0.0% 0.0% 0.0%
CyA + MMF/MPA 0.0% 5.3% 0.0% 1.7% 0.9% 2.9% 0.0% 1.9% 0.7%
Tac + MMF/MPA 0.0% 20.0% 2.9% 27.1% 20.4% 25.0% 0.6% 24.8% 18.0%
--- + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet 0.0% 0.8% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0%
Tac + OtherAntimet 0.0% 2.0% 0.0% 0.4% 0.0% 0.3% 0.2% 1.0% 1.3%
Tac + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + Siro/Evero 0.0% 0.1% 0.0% 0.1% 0.0% 1.7% 0.0% 0.0% 0.0%
CyA + Siro/Evero 0.0% 0.4% 0.0% 0.7% 2.0% 0.3% 0.0% 0.5% 0.0%
Tac + Siro/Evero 0.0% 1.1% 0.7% 1.1% 3.2% 1.2% 0.0% 5.3% 5.3%
--- + MMF/MPA + Siro/Evero 0.0% 0.4% 0.0% 1.2% 0.7% 1.8% 0.1% 1.5% 0.7%
CyA + MMF/MPA + Siro/Evero 0.0% 0.2% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.7%
Tac + MMF/MPA + Siro/Evero 0.0% 0.5% 0.0% 0.6% 3.8% 0.3% 0.1% 7.8% 10.7%
--- + OtherAntimet + Siro/Evero 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + Steroids 0.0% 0.1% 0.7% 0.2% 0.3% 1.0% 0.3% 0.0% 0.7%
CyA + Steroids 0.0% 1.0% 0.0% 0.4% 0.1% 1.0% 2.3% 0.0% 0.0%
Tac + Steroids 42.3% 2.4% 54.0% 4.1% 4.6% 12.6% 13.3% 2.9% 27.3%
--- + MMF/MPA + Steroids 0.0% 0.3% 0.0% 0.9% 0.4% 0.4% 0.3% 0.5% 0.0%
CyA + MMF/MPA + Steroids 7.7% 16.1% 0.0% 5.3% 2.6% 1.5% 3.7% 1.9% 0.0%
Tac + MMF/MPA + Steroids 38.5% 36.6% 5.8% 46.0% 53.8% 15.2% 48.6% 45.6% 22.0%
--- + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.0% 0.0%
CyA + OtherAntimet + Steroids 0.0% 0.6% 0.0% 0.2% 0.3% 0.1% 2.9% 0.0% 0.7%
Tac + OtherAntimet + Steroids 7.7% 1.6% 1.4% 1.2% 0.9% 0.3% 18.5% 0.5% 0.0%
--- + Siro/Evero + Steroids 0.0% 0.3% 1.4% 0.4% 0.3% 0.9% 0.1% 0.0% 0.0%
CyA + Siro/Evero + Steroids 0.0% 2.4% 0.0% 0.9% 0.8% 0.1% 0.1% 0.0% 0.7%
Tac + Siro/Evero + Steroids 0.0% 0.9% 3.6% 1.0% 2.5% 0.8% 2.8% 1.5% 2.0%
Other Regimen 3.8% 3.8% 1.4% 3.8% 1.1% 1.5% 5.7% 2.9% 2.0%


Source: OPTN/SRTR Data as of May 4, 2009.

Percentages are calculated based on the total number of patients with functioning graft and having any immunosuppression information reported at 1yr post-transplant.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF/MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.



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