Table 5.6h

Persistency of Discharge Regimen by Follow-up Period, 2000 to 2004

Recipients with Kidney Transplants

  Year of Transplant
2000 2001 2002 2003 2004
Discharge Regimen (w/ or w/o Steroid Use) CyA+Aza At Discharge (N) 456 296 113 61 35
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 72.3% 65.5% 53.1% 60.7% 84.8%
1 Year PostTx (%) 58.9% 47.0% 38.9% 48.9% 84.8%
2 Years PostTx (%) 48.3% 38.4% 30.1% 35.9% -
3 Years PostTx (%) 35.5% 31.5% 28.9% 35.9% -
CyA+MMF At Discharge (N) 4,810 3,880 3,269 2,852 2,435
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 81.4% 80.7% 80.8% 78.5% 85.3%
1 Year PostTx (%) 71.9% 72.2% 70.5% 69.7% 75.6%
2 Years PostTx (%) 61.9% 62.0% 61.5% 61.1% 62.2%
3 Years PostTx (%) 53.3% 55.9% 55.9% 56.2% -
CyA+Siro At Discharge (N) 627 506 380 445 399
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 73.9% 74.4% 80.5% 75.1% 82.1%
1 Year PostTx (%) 63.2% 63.0% 70.8% 64.2% 72.3%
2 Years PostTx (%) 49.7% 49.7% 62.3% 54.6% 41.7%
3 Years PostTx (%) 37.7% 41.2% 48.8% 33.6% -
Siro+MMF At Discharge (N) 155 422 526 458 419
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 70.2% 65.6% 67.2% 63.4% 76.3%
1 Year PostTx (%) 62.8% 52.1% 58.3% 53.9% 57.8%
2 Years PostTx (%) 51.4% 45.5% 49.0% 48.0% 54.2%
3 Years PostTx (%) 46.6% 35.0% 41.9% 44.1% -
Tac+Aza At Discharge (N) 142 186 158 134 79
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 61.6% 70.3% 55.4% 42.5% 63.7%
1 Year PostTx (%) 53.8% 55.6% 34.3% 35.8% 52.4%
2 Years PostTx (%) 41.2% 42.2% 26.1% 32.9% 0.0%
3 Years PostTx (%) 24.4% 36.5% 19.0% - 0.0%
Tac+MMF At Discharge (N) 4,180 5,522 6,892 7,746 9,268
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 82.1% 83.6% 81.9% 83.7% 88.2%
1 Year PostTx (%) 72.7% 75.1% 73.0% 75.9% 80.9%
2 Years PostTx (%) 62.0% 63.4% 64.8% 68.6% 76.4%
3 Years PostTx (%) 52.9% 57.6% 58.4% 63.5% -
Tac+Siro At Discharge (N) 628 1,049 876 940 794
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 73.7% 78.2% 79.8% 74.4% 74.1%
1 Year PostTx (%) 61.0% 66.9% 64.1% 63.5% 60.4%
2 Years PostTx (%) 47.0% 52.0% 52.1% 54.2% 60.4%
3 Years PostTx (%) 35.5% 42.9% 43.9% 50.4% -


Source: OPTN/SRTR Data as of May 1, 2006.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen(CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up peroid, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.