Table 12.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1996 to 2005

Recipients with Lung Transplants

  Year of Transplant
1996 1997 1998 1999 2000 2001 2002 2003 2004 2005
Functioning Graft at Discharge 697 798 753 800 859 951 944 1,010 1,108 1,293
With Immunosuppression Info 629 792 751 788 854 948 939 1,006 1,098 1,269
Corticosteroids Any in Category 97.1% 98.7% 97.3% 98.1% 97.8% 98.9% 98.6% 94.4% 97.2% 97.9%
Steroids 97.1% 98.7% 97.3% 98.1% 97.8% 98.9% 98.6% 94.4% 97.2% 97.9%
Cyclosporine Any in Category 70.7% 74.5% 73.4% 66.6% 61.9% 52.1% 42.5% 34.7% 29.7% 22.1%
Cyclosporin 2.2% 0.0% 0.0% 0.0% 0.0% 0.4% 0.2% 0.2% 0.2% 0.5%
Sandimmmune 19.4% 16.4% 11.9% 10.8% 6.9% 5.7% 4.5% 4.8% 2.1% 1.7%
Neoral 49.1% 58.1% 61.5% 55.7% 54.0% 39.3% 31.0% 23.1% 20.4% 15.0%
Gengraf 0.0% 0.0% 0.0% 0.0% 1.1% 6.2% 6.7% 6.6% 6.7% 4.8%
Eon 0.0% 0.0% 0.0% 0.1% 0.0% 0.4% 0.1% 0.1% 0.3% 0.2%
Tacrolimus Any in Category 21.0% 24.9% 26.6% 29.9% 38.3% 49.4% 57.2% 65.3% 69.9% 76.2%
Tacrolimus 21.0% 24.9% 26.6% 29.9% 38.3% 49.4% 57.2% 65.3% 69.9% 76.2%
Antimetabolites Any in Category 90.1% 91.0% 92.1% 91.8% 93.7% 91.8% 91.1% 90.0% 90.6% 91.9%
Mycophenolate Mofetil 9.7% 18.9% 22.1% 27.5% 35.6% 41.2% 45.2% 43.7% 46.7% 51.4%
Mycophenolate Sodium 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 2.1%
Azathioprine 80.4% 72.0% 69.9% 64.0% 57.8% 50.3% 45.7% 46.2% 43.9% 38.3%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0% 0.1%
Cytoxan 0.0% 0.1% 0.1% 0.3% 0.1% 0.1% 0.2% 0.0% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 0.1% 0.1% 0.6% 2.6% 4.1% 1.9% 1.1% 1.3% 0.6%
Sirolimus 0.0% 0.1% 0.1% 0.6% 2.6% 4.1% 1.9% 1.1% 1.3% 0.6%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 1, 2006.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients maybe prescribed more than one drug within the same category.