Table 8.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1994 to 2003

Recipients with Kidney-Pancreas Transplants

  Transplant Year
1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Transplants 748 919 861 853 972 943 914 891 905 870
Functioning Graft at 1 Year PostTx 649 825 775 781 871 861 840 818 823 775
With Maintenance Use Recorded at 1 Year PostTx 44 79 82 180 631 841 809 798 798 770
--- + MMF/MPA 4.5% 7.6% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.1% 0.4%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 1.6%
--- + MMF/MPA + Steroids 0.0% 0.0% 0.0% 0.6% 0.6% 0.4% 0.4% 0.4% 0.5% 0.4%
--- + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1%
--- + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.2% 0.0% 0.1% 0.1% 0.4% 0.3%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.5% 0.3% 0.3% 0.6%
--- + Steroids 0.0% 0.0% 0.0% 0.0% 0.3% 0.2% 0.4% 0.1% 1.4% 0.6%
CyA 4.5% 5.1% 0.0% 0.0% 0.2% 0.1% 0.0% 0.1% 0.3% 0.0%
CyA + MMF/MPA 0.0% 1.3% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.3% 0.5%
CyA + MMF/MPA + Steroids 4.5% 12.7% 20.7% 28.9% 23.9% 18.5% 11.5% 8.3% 8.8% 6.6%
CyA + OtherAntimet + Steroids 29.5% 22.8% 9.8% 5.0% 1.9% 0.1% 0.4% 0.1% 0.4% 0.0%
CyA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.1% 0.0% 1.0%
CyA + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.5% 3.0% 2.5% 1.1% 1.6%
CyA + Steroids 2.3% 3.8% 4.9% 1.1% 1.6% 1.9% 1.7% 1.1% 0.5% 0.4%
Tac 4.5% 0.0% 1.2% 1.1% 1.0% 0.5% 0.1% 1.5% 2.9% 1.7%
Tac + MMF/MPA 0.0% 2.5% 0.0% 0.0% 0.6% 1.0% 2.7% 2.1% 4.9% 6.4%
Tac + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.0% 0.0%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 1.5% 0.9% 1.0%
Tac + MMF/MPA + Steroids 0.0% 11.4% 40.2% 47.8% 54.8% 57.7% 56.1% 52.0% 50.4% 52.1%
Tac + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1%
Tac + OtherAntimet + Steroids 0.0% 5.1% 7.3% 2.2% 3.6% 3.6% 1.7% 0.8% 1.5% 1.6%
Tac + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 3.0% 5.3% 7.3% 8.3%
Tac + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.6% 0.0% 1.5% 6.6% 12.9% 9.9% 5.6%
Tac + Steroids 6.8% 5.1% 6.1% 5.6% 5.1% 5.9% 4.0% 5.1% 4.3% 4.9%
Other Regimen 43.2% 22.8% 9.8% 7.2% 6.2% 7.8% 7.3% 5.4% 4.1% 4.2%


Source: OPTN/SRTR Data as of May 2, 2005.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.