Table 7.6h

Persistency of Discharge Regimen by Follow-up Period, 1999 to 2003

Recipients with Pancreas After Kidney (PAK) Transplants

  Year of Transplant
1999 2000 2001 2002 2003
Discharge Regimen (w/ or w/o Steroid Use) CyA+Aza At Discharge (N) - - - - 1
At Discharge (%) - - - - 100.0%
6 Months PostTx (%) - - - - 0.0%
1 Year PostTx (%) - - - - 0.0%
2 Years PostTx (%) - - - - 0.0%
3 Years PostTx (%) - - - - 0.0%
CyA+MMF At Discharge (N) 22 30 18 25 19
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 54.5% 50.0% 76.7% 62.5% 68.4%
1 Year PostTx (%) 45.5% 29.1% 57.6% 62.5% 57.4%
2 Years PostTx (%) 36.4% 29.1% 25.6% 62.5% 28.7%
3 Years PostTx (%) 31.8% 21.8% 25.6% - -
CyA+Siro At Discharge (N) 2 5 4 7 4
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 100.0% 53.3% 75.0% 100.0% 75.0%
1 Year PostTx (%) 100.0% 53.3% 50.0% 100.0% 50.0%
2 Years PostTx (%) - 53.3% 50.0% 33.3% -
3 Years PostTx (%) - 53.3% - - -
Siro+MMF At Discharge (N) - - 1 1 6
At Discharge (%) - - 100.0% 100.0% 100.0%
6 Months PostTx (%) - - 0.0% 0.0% 83.3%
1 Year PostTx (%) - - 0.0% 0.0% 83.3%
2 Years PostTx (%) - - 0.0% 0.0% -
3 Years PostTx (%) - - 0.0% 0.0% -
Tac+Aza At Discharge (N) 4 5 2 1 1
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 50.0% 20.0% 50.0% 0.0% 100.0%
1 Year PostTx (%) 50.0% 0.0% 0.0% 0.0% 0.0%
2 Years PostTx (%) 50.0% 0.0% 0.0% 0.0% 0.0%
3 Years PostTx (%) 50.0% 0.0% 0.0% 0.0% 0.0%
Tac+MMF At Discharge (N) 144 185 180 207 208
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 78.3% 78.6% 81.5% 79.4% 74.2%
1 Year PostTx (%) 67.6% 65.0% 74.1% 63.6% 63.3%
2 Years PostTx (%) 55.5% 57.5% 61.7% 54.3% 63.3%
3 Years PostTx (%) 49.9% 47.5% 55.1% 31.0% -
Tac+Siro At Discharge (N) 2 15 47 46 26
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 50.0% 66.7% 83.0% 70.6% 65.4%
1 Year PostTx (%) 50.0% 60.0% 70.2% 51.8% 52.4%
2 Years PostTx (%) 50.0% 33.3% 63.6% 37.0% 0.0%
3 Years PostTx (%) 50.0% 33.3% 57.5% 37.0% 0.0%


Source: OPTN/SRTR Data as of May 2, 2005.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen(CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up peroid, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.