Table 7.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1994 to 2003

Recipients with Pancreas After Kidney (PAK) Transplants

  Transplant Year
1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Transplants 54 67 113 130 157 221 303 307 377 343
Functioning Graft at 1 Year PostTx 37 41 71 89 111 168 218 247 274 257
With Maintenance Use Recorded at 1 Year PostTx 2 2 3 19 71 164 210 244 269 249
--- + MMF/MPA 50.0% 50.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 1.6%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8%
--- + MMF/MPA + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.6% 0.5% 0.4% 0.4% 0.4%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.6% 0.5% 0.8% 0.4% 0.4%
--- + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.5% 0.0% 0.0% 0.4%
CyA 0.0% 50.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.7% 0.8%
CyA + MMF/MPA + Steroids 0.0% 0.0% 33.3% 10.5% 22.5% 9.1% 8.1% 8.6% 9.7% 4.8%
CyA + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 0.0% 0.0%
CyA + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.0% 1.4% 0.6% 0.5% 0.0% 0.4% 0.0%
CyA + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 1.4% 1.8% 2.9% 1.2% 1.9% 0.8%
CyA + Steroids 0.0% 0.0% 0.0% 0.0% 1.4% 0.0% 1.0% 0.4% 0.4% 1.2%
Tac 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 1.0% 0.0% 1.1% 1.6%
Tac + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.0% 1.2% 2.9% 4.1% 3.3% 7.6%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.4% 1.2%
Tac + MMF/MPA + Steroids 0.0% 0.0% 66.7% 73.7% 64.8% 73.2% 54.3% 54.9% 53.2% 46.2%
Tac + OtherAntimet 0.0% 0.0% 0.0% 0.0% 1.4% 0.0% 1.0% 0.0% 0.0% 0.8%
Tac + OtherAntimet + Steroids 0.0% 0.0% 0.0% 10.5% 4.2% 4.3% 2.4% 0.8% 0.4% 1.6%
Tac + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 1.0% 4.1% 7.4% 4.0%
Tac + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 3.7% 14.8% 15.2% 10.8% 9.6%
Tac + Steroids 0.0% 0.0% 0.0% 5.3% 1.4% 3.7% 4.8% 4.5% 4.1% 3.2%
Other Regimen 50.0% 0.0% 0.0% 0.0% 1.4% 1.2% 4.3% 4.1% 5.2% 12.9%


Source: OPTN/SRTR Data as of May 2, 2005.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.