Table 6.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1994 to 2003

Recipients with Pancreas Transplant Alone (PTA) Transplants

  Transplant Year
1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Transplants 40 42 52 79 88 137 135 165 177 159
Functioning Graft at 1 Year PostTx 24 23 30 46 63 107 97 122 138 117
With Maintenance Use Recorded at 1 Year PostTx 2 2 2 5 51 106 94 120 137 117
--- + MMF/MPA 0.0% 50.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 1.5% 9.4%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.9%
--- + MMF/MPA + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 1.9% 1.1% 0.0% 1.5% 0.9%
--- + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 1.7% 0.7% 0.9%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 2.1% 0.0% 0.7% 0.0%
--- + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8% 0.7% 0.0%
CyA 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 1.1% 0.0% 0.0% 0.0%
CyA + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.8% 1.5% 0.9%
CyA + MMF/MPA + Steroids 0.0% 0.0% 0.0% 0.0% 5.9% 5.7% 3.2% 4.2% 2.9% 2.6%
CyA + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.0% 2.0% 0.9% 0.0% 0.0% 0.0% 0.0%
CyA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.7% 1.7%
CyA + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.9% 0.0% 0.0% 0.7% 1.7%
CyA + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.7% 0.9%
Tac 0.0% 0.0% 0.0% 0.0% 0.0% 1.9% 2.1% 10.8% 4.4% 17.1%
Tac + MMF/MPA 0.0% 0.0% 0.0% 0.0% 0.0% 3.8% 2.1% 2.5% 9.5% 6.8%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.9%
Tac + MMF/MPA + Steroids 50.0% 0.0% 100.0% 40.0% 74.5% 67.0% 53.2% 55.0% 38.0% 23.9%
Tac + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.9%
Tac + OtherAntimet + Steroids 0.0% 0.0% 0.0% 0.0% 7.8% 0.9% 4.3% 0.8% 0.0% 0.0%
Tac + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 1.9% 2.1% 0.8% 9.5% 7.7%
Tac + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.0% 7.5% 12.8% 6.7% 11.7% 6.0%
Tac + Steroids 0.0% 0.0% 0.0% 60.0% 9.8% 4.7% 9.6% 15.0% 13.1% 11.1%
Other Regimen 50.0% 50.0% 0.0% 0.0% 0.0% 2.8% 6.4% 0.8% 2.2% 6.0%


Source: OPTN/SRTR Data as of May 2, 2005.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.