Table 5.6h

Persistency of Discharge Regimen by Follow-up Period, 1999 to 2003

Recipients with Kidney Transplants

  Year of Transplant
1999 2000 2001 2002 2003
Discharge Regimen (w/ or w/o Steroid Use) CyA+Aza At Discharge (N) 684 456 294 113 61
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 67.7% 72.3% 65.1% 53.1% 60.0%
1 Year PostTx (%) 56.8% 58.9% 46.9% 38.9% 45.7%
2 Years PostTx (%) 45.5% 48.3% 37.9% 29.5% 22.9%
3 Years PostTx (%) 35.8% 35.5% 30.3% 29.5% -
CyA+MMF At Discharge (N) 5,666 4,810 3,879 3,268 2,854
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 78.8% 81.3% 80.7% 80.8% 78.5%
1 Year PostTx (%) 68.6% 71.9% 72.2% 70.5% 70.0%
2 Years PostTx (%) 58.9% 61.9% 61.9% 61.2% 60.5%
3 Years PostTx (%) 51.1% 53.4% 56.0% 57.9% -
CyA+Siro At Discharge (N) 210 626 506 380 445
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 71.4% 73.7% 74.5% 80.5% 75.7%
1 Year PostTx (%) 56.4% 63.1% 63.2% 70.7% 65.0%
2 Years PostTx (%) 45.0% 49.8% 50.0% 61.9% 50.3%
3 Years PostTx (%) 36.2% 37.6% 39.6% 30.9% -
Siro+MMF At Discharge (N) 11 154 422 527 458
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 50.0% 70.0% 65.6% 67.0% 63.5%
1 Year PostTx (%) 40.0% 63.3% 52.1% 58.3% 54.1%
2 Years PostTx (%) 30.0% 51.7% 45.7% 49.9% 43.4%
3 Years PostTx (%) 20.0% 46.8% 35.0% 32.9% -
Tac+Aza At Discharge (N) 169 142 186 158 134
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 60.4% 61.6% 70.3% 55.4% 42.9%
1 Year PostTx (%) 50.5% 53.8% 54.9% 34.3% 37.7%
2 Years PostTx (%) 44.1% 41.2% 41.9% 25.7% -
3 Years PostTx (%) 33.8% 24.0% 35.3% - -
Tac+MMF At Discharge (N) 3,356 4,170 5,515 6,883 7,734
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 81.0% 82.2% 83.6% 81.8% 83.5%
1 Year PostTx (%) 71.0% 72.7% 75.0% 72.9% 75.3%
2 Years PostTx (%) 62.1% 62.1% 63.3% 63.4% 64.8%
3 Years PostTx (%) 53.8% 53.0% 56.8% 54.8% -
Tac+Siro At Discharge (N) 29 625 1,049 876 940
At Discharge (%) 100.0% 100.0% 100.0% 100.0% 100.0%
6 Months PostTx (%) 62.1% 73.5% 78.0% 79.7% 74.4%
1 Year PostTx (%) 44.8% 60.4% 66.9% 64.0% 63.0%
2 Years PostTx (%) 20.7% 46.0% 51.9% 52.0% 50.6%
3 Years PostTx (%) 13.8% 34.8% 40.9% 42.8% -


Source: OPTN/SRTR Data as of May 2, 2005.

Regimen change is defined as being on different drug combination at follow-up comparing to discharge, or indication of conflicting regimen(CyA vs. Tac; MMF/MPA vs. Aza; Siro vs. Evero) during follow-up peroid, or graft failure/death. Addition or deletion of steroids is not considered a regimen change.Rates are calculated for the most common discharge regimens.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine; Siro: Sirolimus.

See Technical Notes for further details.