Table 5.6f

Immunosuppression Use for Maintenance by Regimen

One Year Following Transplantation, 1994 to 2003

Recipients with Kidney Transplants

  Transplant Year
1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Transplants 10,646 11,078 11,398 11,701 12,446 12,756 13,611 14,263 14,777 15,134
Functioning Graft at 1 Year PostTx 8,900 9,463 9,904 10,233 10,824 11,045 11,841 12,726 13,251 13,484
With Maintenance Use Recorded at 1 Year PostTx 291 635 807 1,535 6,743 10,467 11,218 12,488 12,929 13,124
--- + MMF/MPA 11.7% 5.7% 1.5% 1.7% 0.3% 0.1% 0.0% 0.1% 0.1% 0.2%
--- + MMF/MPA + OtherAntimet 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.3% 0.5% 1.1%
--- + MMF/MPA + Steroids 0.3% 0.6% 0.9% 0.8% 1.2% 1.5% 0.9% 0.9% 0.9% 0.8%
--- + OtherAntimet 2.7% 0.0% 0.1% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
--- + OtherAntimet + Steroids 0.3% 0.5% 0.6% 0.1% 0.2% 0.2% 0.1% 0.1% 0.1% 0.1%
--- + Siro/Evero 1.0% 0.8% 0.0% 0.3% 0.1% 0.1% 0.2% 0.2% 0.1% 0.1%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.2% 0.3% 0.5% 0.7% 0.7% 0.6%
--- + Steroids 0.7% 0.5% 3.3% 2.3% 0.7% 0.5% 0.6% 0.7% 0.5% 0.4%
CyA 1.0% 0.5% 0.1% 0.3% 0.3% 0.7% 0.7% 0.1% 0.1% 0.1%
CyA + MMF/MPA 0.0% 0.6% 1.2% 0.9% 0.9% 0.5% 1.0% 1.1% 1.6% 2.1%
CyA + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.2% 0.0% 0.1% 0.1%
CyA + MMF/MPA + Steroids 3.8% 16.7% 33.6% 37.0% 41.5% 39.2% 31.7% 24.2% 19.9% 15.3%
CyA + OtherAntimet 1.0% 0.5% 0.4% 0.0% 0.3% 0.2% 0.1% 0.0% 0.0% 0.0%
CyA + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
CyA + OtherAntimet + Steroids 28.2% 30.6% 11.4% 5.7% 5.6% 5.4% 3.0% 1.7% 0.9% 0.5%
CyA + Siro/Evero 0.3% 0.2% 0.1% 0.0% 0.0% 0.2% 0.3% 0.2% 0.8% 1.0%
CyA + Siro/Evero + Steroids 0.7% 0.0% 0.9% 1.5% 2.5% 2.1% 4.0% 3.3% 2.7% 2.0%
CyA + Steroids 12.0% 12.0% 11.5% 10.6% 7.8% 6.6% 4.3% 2.5% 1.6% 1.5%
Tac 1.7% 0.5% 0.6% 0.8% 0.5% 0.5% 0.5% 1.1% 1.8% 2.1%
Tac + MMF/MPA 0.0% 0.2% 1.2% 2.3% 1.4% 1.7% 1.8% 2.8% 5.7% 8.4%
Tac + MMF/MPA + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.3% 0.3% 0.4% 0.8%
Tac + MMF/MPA + Steroids 0.0% 4.9% 12.5% 17.7% 24.5% 28.3% 31.4% 37.5% 39.7% 42.4%
Tac + OtherAntimet 0.0% 0.0% 0.1% 0.0% 0.1% 0.1% 0.2% 0.1% 0.1% 0.2%
Tac + OtherAntimet + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Tac + OtherAntimet + Steroids 5.8% 2.5% 2.5% 2.5% 2.6% 2.2% 1.9% 2.0% 1.5% 1.3%
Tac + Siro/Evero 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.7% 1.5% 2.2% 2.4%
Tac + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.1% 1.0% 4.7% 7.2% 5.9% 5.1%
Tac + Steroids 4.1% 5.4% 7.2% 6.3% 6.3% 5.9% 6.3% 5.8% 5.7% 4.9%
Other Regimen 24.4% 17.6% 10.2% 9.3% 2.8% 2.8% 4.4% 5.5% 6.4% 6.4%


Source: OPTN/SRTR Data as of May 2, 2005.

Percentages are calculated based on the total number of patients with maintenance use at one year following transplantation. They sum to 100 percent for each column.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.