Table 15.12

Immunosuppression Use for Maintenance by Regimen

Two Years Following Transplantation, 1998 to 2002

Recipients with Intestine Transplants

  Transplant Year
1998 1999 2000 2001 2002
Transplants 70 73 81 111 107
Functioning Graft at 2 Years PostTx 29 30 46 58 64
With Maintenance Use Recorded at 2 Years PostTx 29 30 46 58 64
--- + Siro/Evero 0.0% 0.0% 0.0% 0.0% 1.6%
--- + Siro/Evero + Steroids 0.0% 0.0% 0.0% 0.0% 0.0%
--- + Steroids 0.0% 0.0% 0.0% 0.0% 1.6%
Tac 10.3% 3.3% 2.2% 29.3% 21.9%
Tac + MMF/MPA 0.0% 0.0% 0.0% 0.0% 1.6%
Tac + MMF/MPA + Steroids 13.8% 6.7% 8.7% 1.7% 4.7%
Tac + OtherAntimet + Steroids 0.0% 13.3% 0.0% 0.0% 0.0%
Tac + Siro/Evero 0.0% 3.3% 0.0% 1.7% 3.1%
Tac + Siro/Evero + Steroids 0.0% 6.7% 23.9% 8.6% 20.3%
Tac + Steroids 41.4% 63.3% 65.2% 58.6% 42.2%
Other Regimen 34.5% 3.3% 0.0% 0.0% 3.1%


Source: OPTN/SRTR Data as of May 2, 2005.

Percentages are calculated based on the total number of patients with maintenance use at two years following transplantation. They sum to 100 percent for each column.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

---: No Calcineurin Inhibitor Use; CyA: Cyclosporine; Tac: Tacrolimus.

MMF: Mycophenolate Mofetil; MPA: Mycophenolate Sodium; Siro: Sirolimus; Evero: Everolimus; OtherAntimet: Antimetabolites excluding MMF and MPA.

"Other Regimen" includes drug combinations that are different from the listed regimens and drugs from the text field entering.