Table 15.5b

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2002

Recipients of Living Donor Livers

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002
Total Patients 48 133 242 341 237
Steroids Withdrawn 17 60 131 222 149
Rate 35.4% 45.1% 54.1% 65.1% 62.9%
CyA Patients 5 10 13 5 5
Steroids Withdrawn 1 6 9 3 5
Rate 20.0% 60.0% 69.2% 60.0% 100.0%
Tac Patients 17 63 92 121 90
Steroids Withdrawn 10 29 49 76 60
Rate 58.8% 46.0% 53.3% 62.8% 66.7%
CyA+MMF Patients 5 7 13 20 13
Steroids Withdrawn 1 4 4 16 10
Rate 20.0% 57.1% 30.8% 80.0% 76.9%
Tac+MMF Patients 17 37 90 142 98
Steroids Withdrawn 3 17 52 98 57
Rate 17.6% 45.9% 57.8% 69.0% 58.2%
CyA+Aza Patients 1 3 3 1 4
Steroids Withdrawn 0 0 1 0 2
Rate 0.0% 0.0% 33.3% 0.0% 50.0%
Tac+Aza Patients - 4 2 - 2
Steroids Withdrawn - 1 1 - 2
Rate - 25.0% 50.0% - 100.0%
Siro+MMF Patients - - 1 3 2
Steroids Withdrawn - - 0 0 2
Rate - - 0.0% 0.0% 100.0%
CyA+Siro Patients - - 2 3 1
Steroids Withdrawn - - 1 3 1
Rate - - 50.0% 100.0% 100.0%
Tac+Siro Patients - - 10 22 9
Steroids Withdrawn - - 7 13 5
Rate - - 70.0% 59.1% 55.6%
Other Regimen Patients 3 9 16 24 13
Steroids Withdrawn 2 3 7 13 5
Rate 66.7% 33.3% 43.8% 54.2% 38.5%


Source: OPTN/SRTR Data as of May 2, 2005.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioninggraft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;Siro: Sirolimus.