Table 15.5b

Steroid Withdrawal Rate at One Year Following Transplantation, 1999 to 2003

Recipients of Living Donor Livers

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003
Total Patients 149 258 365 252 195
Steroids Withdrawn 36 81 164 122 92
Rate 24.2% 31.4% 44.9% 48.4% 47.2%
CyA Patients 10 14 7 5 6
Steroids Withdrawn 1 3 4 3 2
Rate 10.0% 21.4% 57.1% 60.0% 33.3%
Tac Patients 75 99 131 93 67
Steroids Withdrawn 25 33 59 44 28
Rate 33.3% 33.3% 45.0% 47.3% 41.8%
CyA+MMF Patients 10 17 20 16 13
Steroids Withdrawn 2 3 10 10 11
Rate 20.0% 17.6% 50.0% 62.5% 84.6%
Tac+MMF Patients 37 92 151 105 99
Steroids Withdrawn 6 25 65 55 49
Rate 16.2% 27.2% 43.0% 52.4% 49.5%
CyA+Aza Patients 3 3 1 4 2
Steroids Withdrawn 0 1 0 0 1
Rate 0.0% 33.3% 0.0% 0.0% 50.0%
Tac+Aza Patients 4 2 - 2 -
Steroids Withdrawn 1 1 - 1 -
Rate 25.0% 50.0% - 50.0% -
Siro+MMF Patients - 1 4 2 1
Steroids Withdrawn - 0 2 2 0
Rate - 0.0% 50.0% 100.0% 0.0%
CyA+Siro Patients - 3 3 1 -
Steroids Withdrawn - 3 2 1 -
Rate - 100.0% 66.7% 100.0% -
Tac+Siro Patients - 12 23 9 1
Steroids Withdrawn - 5 10 4 0
Rate - 41.7% 43.5% 44.4% 0.0%
Other Regimen Patients 10 15 25 15 6
Steroids Withdrawn 1 7 12 2 1
Rate 10.0% 46.7% 48.0% 13.3% 16.7%


Source: OPTN/SRTR Data as of May 2, 2005.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioninggraft and maintenance drug use one year after transplantation.

Transplants prior to year 1999 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;Siro: Sirolimus.