Table 15.5a

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2002

Recipients of Deceased Donor Livers

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002
Total Patients 2,481 2,484 2,813 2,773 2,961
Steroids Withdrawn 1,166 1,345 1,728 1,805 1,970
Rate 47.0% 54.1% 61.4% 65.1% 66.5%
CyA Patients 375 268 180 88 69
Steroids Withdrawn 121 125 101 57 53
Rate 32.3% 46.6% 56.1% 64.8% 76.8%
Tac Patients 921 1,010 968 988 1,175
Steroids Withdrawn 511 592 657 678 794
Rate 55.5% 58.6% 67.9% 68.6% 67.6%
CyA+MMF Patients 190 240 208 170 131
Steroids Withdrawn 71 108 88 89 72
Rate 37.4% 45.0% 42.3% 52.4% 55.0%
Tac+MMF Patients 536 639 944 1,090 1,205
Steroids Withdrawn 307 389 588 704 812
Rate 57.3% 60.9% 62.3% 64.6% 67.4%
CyA+Aza Patients 170 118 95 46 38
Steroids Withdrawn 40 38 47 30 20
Rate 23.5% 32.2% 49.5% 65.2% 52.6%
Tac+Aza Patients 143 81 59 58 72
Steroids Withdrawn 48 29 24 32 46
Rate 33.6% 35.8% 40.7% 55.2% 63.9%
Siro+MMF Patients - 2 23 38 32
Steroids Withdrawn - 0 17 28 22
Rate - 0.0% 73.9% 73.7% 68.8%
CyA+Siro Patients 18 2 10 7 21
Steroids Withdrawn 15 2 7 3 14
Rate 83.3% 100.0% 70.0% 42.9% 66.7%
Tac+Siro Patients - 4 129 118 84
Steroids Withdrawn - 1 84 84 65
Rate - 25.0% 65.1% 71.2% 77.4%
Other Regimen Patients 128 120 197 170 134
Steroids Withdrawn 53 61 115 100 72
Rate 41.4% 50.8% 58.4% 58.8% 53.7%


Source: OPTN/SRTR Data as of May 2, 2005.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioninggraft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;Siro: Sirolimus.