Table 15.5a

Steroid Withdrawal Rate at One Year Following Transplantation, 1999 to 2003

Recipients of Deceased Donor Livers

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003
Total Patients 2,681 2,895 2,997 3,232 3,210
Steroids Withdrawn 861 1,147 1,373 1,665 1,632
Rate 32.1% 39.6% 45.8% 51.5% 50.8%
CyA Patients 289 193 92 75 50
Steroids Withdrawn 70 45 41 41 17
Rate 24.2% 23.3% 44.6% 54.7% 34.0%
Tac Patients 1,074 997 1,076 1,267 1,140
Steroids Withdrawn 428 470 525 699 594
Rate 39.9% 47.1% 48.8% 55.2% 52.1%
CyA+MMF Patients 271 224 188 150 140
Steroids Withdrawn 59 52 60 63 57
Rate 21.8% 23.2% 31.9% 42.0% 40.7%
Tac+MMF Patients 702 957 1,171 1,330 1,550
Steroids Withdrawn 239 391 544 684 824
Rate 34.0% 40.9% 46.5% 51.4% 53.2%
CyA+Aza Patients 123 97 47 44 1
Steroids Withdrawn 3 15 4 12 0
Rate 2.4% 15.5% 8.5% 27.3% 0.0%
Tac+Aza Patients 87 63 59 77 80
Steroids Withdrawn 11 10 15 17 15
Rate 12.6% 15.9% 25.4% 22.1% 18.8%
Siro+MMF Patients 2 27 39 34 32
Steroids Withdrawn 0 11 16 20 16
Rate 0.0% 40.7% 41.0% 58.8% 50.0%
CyA+Siro Patients 3 13 8 22 19
Steroids Withdrawn 1 7 3 14 10
Rate 33.3% 53.8% 37.5% 63.6% 52.6%
Tac+Siro Patients 4 135 134 85 42
Steroids Withdrawn 2 63 67 57 24
Rate 50.0% 46.7% 50.0% 67.1% 57.1%
Other Regimen Patients 126 189 183 148 156
Steroids Withdrawn 48 83 98 58 75
Rate 38.1% 43.9% 53.6% 39.2% 48.1%


Source: OPTN/SRTR Data as of May 2, 2005.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioninggraft and maintenance drug use one year after transplantation.

Transplants prior to year 1999 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;Siro: Sirolimus.