Table 15.4b

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2002

Recipients of Living Donor Kidneys

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002
Total Patients 2,997 3,256 3,862 4,081 4,073
Steroids Withdrawn 201 184 270 384 538
Rate 6.7% 5.7% 7.0% 9.4% 13.2%
CyA Patients 190 196 141 92 60
Steroids Withdrawn 13 11 10 12 3
Rate 6.8% 5.6% 7.1% 13.0% 5.0%
Tac Patients 75 92 146 148 124
Steroids Withdrawn 11 13 21 24 16
Rate 14.7% 14.1% 14.4% 16.2% 12.9%
CyA+MMF Patients 1,543 1,664 1,641 1,351 1,067
Steroids Withdrawn 77 74 57 75 82
Rate 5.0% 4.4% 3.5% 5.6% 7.7%
Tac+MMF Patients 556 792 1,124 1,610 2,034
Steroids Withdrawn 39 50 96 165 267
Rate 7.0% 6.3% 8.5% 10.2% 13.1%
CyA+Aza Patients 319 219 163 126 44
Steroids Withdrawn 27 8 7 4 2
Rate 8.5% 3.7% 4.3% 3.2% 4.5%
Tac+Aza Patients 54 52 50 65 73
Steroids Withdrawn 15 10 13 17 17
Rate 27.8% 19.2% 26.0% 26.2% 23.3%
Siro+MMF Patients 2 1 29 89 115
Steroids Withdrawn 0 0 1 2 27
Rate 0.0% 0.0% 3.4% 2.2% 23.5%
CyA+Siro Patients 71 47 227 149 100
Steroids Withdrawn 6 3 26 13 34
Rate 8.5% 6.4% 11.5% 8.7% 34.0%
Tac+Siro Patients - 4 158 280 254
Steroids Withdrawn - 1 14 47 56
Rate - 25.0% 8.9% 16.8% 22.0%
Other Regimen Patients 187 189 183 171 202
Steroids Withdrawn 13 14 25 25 34
Rate 7.0% 7.4% 13.7% 14.6% 16.8%


Source: OPTN/SRTR Data as of May 2, 2005.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioninggraft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;Siro: Sirolimus.