Table 15.4b

Steroid Withdrawal Rate at One Year Following Transplantation, 1999 to 2003

Recipients of Living Donor Kidneys

Discharge Regimen Year of Transplant
1999 2000 2001 2002 2003
Total Patients 3,441 3,893 4,386 4,375 4,088
Steroids Withdrawn 148 185 241 469 484
Rate 4.3% 4.8% 5.5% 10.7% 11.8%
CyA Patients 197 145 104 69 80
Steroids Withdrawn 5 6 4 3 3
Rate 2.5% 4.1% 3.8% 4.3% 3.8%
Tac Patients 97 143 156 134 118
Steroids Withdrawn 8 14 20 17 18
Rate 8.2% 9.8% 12.8% 12.7% 15.3%
CyA+MMF Patients 1,759 1,615 1,458 1,166 896
Steroids Withdrawn 68 48 38 73 44
Rate 3.9% 3.0% 2.6% 6.3% 4.9%
Tac+MMF Patients 846 1,160 1,736 2,159 2,219
Steroids Withdrawn 50 59 103 213 276
Rate 5.9% 5.1% 5.9% 9.9% 12.4%
CyA+Aza Patients 238 163 131 49 17
Steroids Withdrawn 6 4 0 3 0
Rate 2.5% 2.5% 0.0% 6.1% 0.0%
Tac+Aza Patients 57 49 67 74 62
Steroids Withdrawn 1 10 10 13 3
Rate 1.8% 20.4% 14.9% 17.6% 4.8%
Siro+MMF Patients 1 30 89 124 108
Steroids Withdrawn 0 1 0 18 8
Rate 0.0% 3.3% 0.0% 14.5% 7.4%
CyA+Siro Patients 50 231 156 108 100
Steroids Withdrawn 3 13 6 37 32
Rate 6.0% 5.6% 3.8% 34.3% 32.0%
Tac+Siro Patients 4 172 302 277 233
Steroids Withdrawn 0 11 40 54 39
Rate 0.0% 6.4% 13.2% 19.5% 16.7%
Other Regimen Patients 192 185 187 215 255
Steroids Withdrawn 7 19 20 38 61
Rate 3.6% 10.3% 10.7% 17.7% 23.9%


Source: OPTN/SRTR Data as of May 2, 2005.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioninggraft and maintenance drug use one year after transplantation.

Transplants prior to year 1999 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;Siro: Sirolimus.