Table 15.4a

Steroid Withdrawal Rate at Two Years Following Transplantation, 1998 to 2002

Recipients of Deceased Donor Kidneys

Discharge Regimen Year of Transplant
1998 1999 2000 2001 2002
Total Patients 4,960 4,903 5,001 5,178 5,258
Steroids Withdrawn 277 286 285 432 524
Rate 5.6% 5.8% 5.7% 8.3% 10.0%
CyA Patients 292 268 170 77 71
Steroids Withdrawn 12 11 4 8 12
Rate 4.1% 4.1% 2.4% 10.4% 16.9%
Tac Patients 135 137 159 201 195
Steroids Withdrawn 20 14 20 35 33
Rate 14.8% 10.2% 12.6% 17.4% 16.9%
CyA+MMF Patients 2,578 2,433 2,034 1,572 1,376
Steroids Withdrawn 92 87 59 58 72
Rate 3.6% 3.6% 2.9% 3.7% 5.2%
Tac+MMF Patients 899 1,264 1,566 2,124 2,663
Steroids Withdrawn 71 103 125 205 260
Rate 7.9% 8.1% 8.0% 9.7% 9.8%
CyA+Aza Patients 457 285 199 99 44
Steroids Withdrawn 26 18 6 4 1
Rate 5.7% 6.3% 3.0% 4.0% 2.3%
Tac+Aza Patients 96 59 46 74 51
Steroids Withdrawn 7 12 14 9 14
Rate 7.3% 20.3% 30.4% 12.2% 27.5%
Siro+MMF Patients 0 8 63 172 191
Steroids Withdrawn - 0 3 12 21
Rate - 0.0% 4.8% 7.0% 11.0%
CyA+Siro Patients 170 73 247 234 144
Steroids Withdrawn 25 3 9 16 15
Rate 14.7% 4.1% 3.6% 6.8% 10.4%
Tac+Siro Patients - 8 212 310 206
Steroids Withdrawn - 0 16 46 36
Rate - 0.0% 7.5% 14.8% 17.5%
Other Regimen Patients 333 368 305 315 317
Steroids Withdrawn 24 38 29 39 60
Rate 7.2% 10.3% 9.5% 12.4% 18.9%


Source: OPTN/SRTR Data as of May 2, 2005.

Includes patients receiving first transplants of any organ with steroid use at transplant discharge, and who have a functioninggraft and maintenance drug use two years after transplantation.

Transplants prior to year 1998 are not reported due to insufficient reporting of immunosuppressive drug use.

CyA: Cyclosporine; Tac: Tacrolimus; MMF: Include MMF(Mycophenolate Mofetil) and MPA(Mycophenolate Sodium); Aza: Azathioprine;Siro: Sirolimus.