Table 12.6e

Immunosuppression Use for Maintenance

Prior to Discharge, 1995 to 2004

Recipients with Lung Transplants

  Year of Transplant
1995 1996 1997 1998 1999 2000 2001 2002 2003 2004
Functioning Graft at Discharge 773 697 798 754 800 859 952 944 1,011 1,107
With Immunosuppression Info 761 629 792 751 788 854 949 939 1,007 1,094
Corticosteroids Any in Category 97.2% 97.1% 98.7% 97.3% 98.1% 97.8% 98.9% 98.6% 94.4% 97.1%
Steroids 97.2% 97.1% 98.7% 97.3% 98.1% 97.8% 98.9% 98.6% 94.4% 97.1%
Cyclosporine Any in Category 77.0% 70.7% 74.5% 73.4% 66.6% 61.9% 52.1% 42.5% 34.7% 29.7%
Cyclosporin 60.8% 2.2% 0.0% 0.0% 0.0% 0.0% 0.4% 0.2% 0.2% 0.2%
Sandimmmune 11.8% 19.4% 16.4% 11.9% 10.8% 6.9% 5.7% 4.5% 4.8% 2.1%
Neoral 4.3% 49.1% 58.1% 61.5% 55.7% 54.0% 39.3% 31.0% 23.0% 20.4%
Gengraf 0.0% 0.0% 0.0% 0.0% 0.0% 1.1% 6.2% 6.7% 6.6% 6.8%
Eon 0.0% 0.0% 0.0% 0.0% 0.1% 0.0% 0.4% 0.1% 0.1% 0.3%
Tacrolimus Any in Category 9.1% 21.0% 24.9% 26.6% 29.9% 38.3% 49.3% 57.2% 65.3% 69.8%
Tacrolimus 9.1% 21.0% 24.9% 26.6% 29.9% 38.3% 49.3% 57.2% 65.3% 69.8%
Antimetabolites Any in Category 90.8% 90.1% 91.0% 92.1% 91.8% 93.7% 91.7% 91.1% 90.0% 90.6%
Mycophenolate Mofetil 3.2% 9.7% 18.9% 22.1% 27.5% 35.6% 41.2% 45.2% 43.8% 46.5%
Azathioprine 87.5% 80.4% 72.0% 69.9% 64.0% 57.8% 50.3% 45.7% 46.2% 44.1%
Leflunomide 0.0% 0.0% 0.0% 0.0% 0.0% 0.1% 0.1% 0.0% 0.0% 0.0%
Cytoxan 0.1% 0.0% 0.1% 0.1% 0.3% 0.1% 0.1% 0.2% 0.0% 0.0%
mTOR Inhibitors Any in Category 0.0% 0.0% 0.1% 0.1% 0.6% 2.6% 4.1% 1.9% 1.1% 1.4%
Sirolimus 0.0% 0.0% 0.1% 0.1% 0.6% 2.6% 4.1% 1.9% 1.1% 1.4%
Everolimus 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%


Source: OPTN/SRTR Data as of May 2, 2005.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients maybe prescribed more than one drug within the same category.