Table 1.10

Immunosuppression Usage by Organ in 2001 and 2002

  Organ
Kidney PTA PAK KP Liver Intestine Heart Lung Heart-Lung
Induction Use (2002 Transplants) 65.2% 66.9% 72.5% 73.8% 17.6% 56.6% 44.8% 41.1% 59.4%
Induction Drugs (2002 Transplants) ATG 2.0% 0.0% 2.5% 2.6% 0.5% 0.9% 7.1% 6.8% 15.6%
OKT3 1.0% 2.5% 1.4% 0.9% 0.3% 1.9% 5.4% 0.6% 6.3%
Thymoglobulin 25.7% 58.0% 51.2% 36.5% 4.3% 31.1% 16.3% 8.8% 3.1%
Zenapax 13.2% 34.4% 25.9% 16.0% 4.6% 8.5% 11.1% 13.9% 15.6%
Simulect 26.7% 4.5% 8.3% 25.2% 8.0% 14.2% 7.0% 11.5% 18.8%
Maintenance At Transplant Discharge (2002 Transplants) Calcineurin Inhibitor Use   92.8% 98.6% 96.6% 96.0% 96.0% 95.5% 96.6% 98.1% 100.0%
Cyclosporine 30.0% 4.1% 11.6% 9.4% 10.3% 0.0% 60.5% 42.8% 61.9%
Tacrolimus 63.2% 95.3% 86.0% 87.1% 86.7% 95.5% 39.0% 56.7% 42.9%
Antimetabolite Use   81.4% 65.5% 73.8% 80.0% 51.3% 11.2% 83.8% 90.3% 95.2%
Azathioprine 2.3% 1.4% 0.3% 0.9% 3.6% 0.0% 12.4% 46.2% 52.4%
Mycophenolate mofetil 79.3% 64.2% 73.5% 79.2% 47.7% 11.2% 75.0% 45.2% 47.6%
Rapamycin Use 14.7% 15.5% 18.6% 17.5% 6.6% 19.1% 9.8% 1.9% 0.0%
Current Maintenance At End of First Year (2001 Transplants) Calcineurin Inhibitor Use   92.0% 94.6% 97.0% 95.6% 94.3% 98.5% 94.0% 91.9% 100.0%
Cyclosporine 33.7% 5.4% 11.1% 13.4% 14.6% 0.0% 53.8% 31.7% 25.0%
Tacrolimus 58.8% 89.3% 86.4% 82.8% 82.1% 98.5% 40.8% 62.1% 75.0%
Antimetabolite Use   75.1% 67.0% 73.2% 68.9% 30.9% 5.9% 83.1% 77.1% 85.0%
Azathioprine 4.1% 0.9% 1.7% 1.5% 2.8% 2.9% 10.5% 31.5% 35.0%
Mycophenolate mofetil 71.1% 66.1% 71.5% 67.4% 28.3% 2.9% 72.8% 45.5% 50.0%
Rapamycin Use 17.3% 9.8% 22.6% 22.7% 9.8% 10.3% 6.6% 8.7% 0.0%

Source: OPTN/SRTR Data as of August 1, 2003.

Individual drug percentages will not necessarily add up to the drug category percentages, as patients may

be prescribed more than one drug within the same category.

Induction drugs include any reported antilymphocyte antibodies and antibodies directed against lymphocyte receptors.